Question 1

Describe, in short phrases, the three step mechanism by which hexanoyl chloride reacts with dimethylamine.

Accepted Answer

(i) addition of the nucleophil...

Question 2

What reagents are needed to complete the following reaction?

Accepted Answer

The answer of What reagents are needed to complete the...

Question 3

Provide the major organic product in the reaction shown below.

Accepted Answer

The answer of Provide the major organic product in the...

Question 4

Predict the major product of the following reaction.

Accepted Answer

The answer of Predict the major product of the following...

Question 5

Two equivalents of methyl magnesium bromide will add to ________.

Accepted Answer

A)   lactones
B)   aldehydes
C)   ketones
D)   imines
E)   secondary amines

Question 6

Which of the following structures are carboxylic acid derivatives?

Accepted Answer

The answer of Which of the following structures are carboxylic...

Question 7

Provide the major organic product in the reaction shown below.

Accepted Answer

The answer of Provide the major organic product in the...

Question 8

Provide the name of the compound shown below.

Accepted Answer

The answer of Provide the name of the compound shown...

Question 9

Provide the major organic product in the reaction shown below.

Accepted Answer

The answer of Provide the major organic product in the...

Question 10

How could you synthesize 3-phenylpentan-3-ol from benzoic acid?

Accepted Answer

1) SOCl₂ or methanol,...

Question 11

Provide an arrow pushing mechanism for the following reaction. Show all intermediate structures and formal charges. You do not need to show resonance structures.

Accepted Answer

The answer of Provide an arrow pushing mechanism for the...

Question 12

Predict the major product of the following reaction.

Accepted Answer

The answer of Predict the major product of the following...

Question 13

Which of the following compounds is(are)  hydrolyzed to butanoic acid upon heating in

Accepted Answer

A)   ethyl butanoate
B)   butyl acetate
C)   N-methylbutanamide
D)   both A and B
E)   both A and C

Question 14

Phthalic acid produces what acid derivative upon heating?

Accepted Answer

A)   an ester
B)   a carboxylate
C)   an acid chloride
D)   an anhydride
E)   an amide D

Question 15

Show how one might synthesize phenylacetone using toluene, NaCN, and any other necessary reagents.

Accepted Answer

1) Br₂, hν ...

Question 16

Propose a synthesis of benzonitrile from benzene and any other necessary reagents.

Accepted Answer

1) HNO₃, H₂SO₄ 2) Fe, HCl 3) NaNO₂, HCl, cold 4) CuCN

Question 17

Provide the structure of (R)-4-ethoxypentanenitrile.

Accepted Answer

The answer of Provide the structure of (R)-4-ethoxypentanenitrile....

Question 18

Why are β-lactams, such as penicillins and cephalosporins, unusually reactive amides?

Accepted Answer

Their enhanced react...

Question 19

Acids can be converted to primary amines by ________.

Accepted Answer

A)   conversion to the nitrile followed by treatment with LiAlH4
B)   conversion to the diazonium salt followed by treatment with NaBH4
C)   conversion to the primary amide followed by treatment with LiAlH4
D)   both A and B
E)   both A and C

Question 20

Which of the following statements is/are true?

Accepted Answer

A)   Two equivalents of Grignard reagent react with acid chlorides to yield tertiary alcohols after hydrolysis.
B)   LiAlH4 reacts with acid chlorides to yield secondary alcohols after hydrolysis.
C)   LiAlH[OC(CH3) 3]3 reacts with acid chlorides to yield primary alcohols after hydrolysis.
D)   both A and B
E)   both B and C

Exam 21: Carboxylic Acid Derivatives

Describe, in short phrases, the three step mechanism by which hexanoyl chloride reacts with dimethylamine.

Correct Answerverified(i) addition of the nucleophil...View AnswerShow Answer

What reagents are needed to complete the following reaction?

Correct AnswerverifiedShow Answer

Provide the major organic product in the reaction shown below.

Correct AnswerverifiedShow Answer

Predict the major product of the following reaction.

Correct AnswerverifiedShow Answer

Two equivalents of methyl magnesium bromide will add to ________.

Correct AnswerverifiedShow Answer

Which of the following structures are carboxylic acid derivatives?

Correct AnswerverifiedShow Answer

Provide the major organic product in the reaction shown below.

Correct Answerverified11eab5e1_c8fe_4f05_9bae_0f42776b2f2c_TB6199_00

Provide the name of the compound shown below.

Correct AnswerverifiedShow Answer

Provide the major organic product in the reaction shown below.

Correct AnswerverifiedShow Answer

How could you synthesize 3-phenylpentan-3-ol from benzoic acid?

Correct Answerverified1) SOCl2 or methanol,...View AnswerShow Answer

Provide an arrow pushing mechanism for the following reaction. Show all intermediate structures and formal charges. You do not need to show resonance structures.

Correct AnswerverifiedShow Answer

Predict the major product of the following reaction.

Correct AnswerverifiedShow Answer

Which of the following compounds is(are) hydrolyzed to butanoic acid upon heating in

Correct AnswerverifiedShow Answer

Phthalic acid produces what acid derivative upon heating?

Correct AnswerverifiedD

Show how one might synthesize phenylacetone using toluene, NaCN, and any other necessary reagents.

Correct Answerverified1) Br2, hν ...View AnswerShow Answer

Propose a synthesis of benzonitrile from benzene and any other necessary reagents.

Correct Answerverified1) HNO3, H2SO4 2) Fe, HCl 3) NaNO2, HCl, cold 4) CuCN

Provide the structure of (R)-4-ethoxypentanenitrile.

Correct AnswerverifiedShow Answer

Why are β-lactams, such as penicillins and cephalosporins, unusually reactive amides?

Correct AnswerverifiedTheir enhanced react...View AnswerShow Answer

Acids can be converted to primary amines by ________.

Correct AnswerverifiedShow Answer

Which of the following statements is/are true?

Correct AnswerverifiedShow Answer

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(i) addition of the nucleophil...
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11eab5e1_c8fe_4f05_9bae_0f42776b2f2c_TB6199_00

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1) SOCl₂ or methanol,...
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D

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1) Br₂, hν ...
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1) HNO₃, H₂SO₄ 2) Fe, HCl 3) NaNO₂, HCl, cold 4) CuCN

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Their enhanced react...
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