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What change in renal regulation of H+ would help compensate for a metabolic acidosis?


A) a decrease in the filtered load of H+
B) an increase in the urinary pH
C) a decrease in the tubular production of ammonia
D) a decrease in the amount of H+ secreted in the proximal tubule
E) an increase in the production of new plasma HCO3-

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A consequence of lack of vasopressin is excretion of sugar in the urine, which occurs in the condition diabetes mellitus.

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Ingestion of large amounts of K+ triggers reflexes to limit the amount of K+ reabsorbed by the cortical collecting ducts.

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Large amounts of protein in a person's urine indicate that the person is eating a high-protein diet.

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Which of the following most accurately describes the renal transport of Na+?


A) Na+ is actively transported in all segments of the tubule.
B) Primary active transport of Na+ allows for secondary active transport of glucose and H+ in the proximal tubule.
C) Most of the Na+ transport occurs in the distal convoluted tubule and collecting ducts.
D) Na+ is actively secreted into the nephron lumen by cells in the cortical collecting ducts.
E) Na+ is actively transported across the luminal membrane of proximal tubule cells in exchange for K+, by Na+/K+ ATPase pumps.

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Which is TRUE about the juxtaglomerular apparatus?


A) It is composed of parts of the ascending limb of the loop of Henle and the efferent arteriole.
B) It is composed of glomerular capillaries and the macula densa.
C) It is the site of renin secretion.
D) It is created by the junction between the proximal tubule and the afferent arteriole.
E) It is composed of cells that secrete atrial natriuretic peptide and cells that secrete norepinephrine.

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C

What is the rate-limiting (regulated) step for stimulating the secretion of aldosterone?


A) conversion of angiotensin I to angiotensin II in the blood
B) secretion of angiotensinogen by the liver
C) conversion of angiotensinogen to angiotensin I in the blood
D) secretion of ACTH by the anterior pituitary
E) secretion of angiotensin II by the kidney

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Which is NOT true about the countercurrent multiplier system of the kidney?


A) It creates a hyperosmolar medullary interstitium that allows the kidneys to form hypertonic urine.
B) The descending loop of Henle is permeable to water.
C) There is active transport of sodium and chloride out of the ascending limb of the loop of Henle.
D) The ascending loop of Henle is not permeable to water.
E) The fraction of filtered NaCl reabsorbed from the ascending limb equals the fraction of filtered water reabsorbed from the descending limb.

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In what segment of the nephron is the greatest fraction of filtered water reabsorbed?


A) the proximal tubule
B) the ascending limb of the loop of Henle
C) the distal convoluted tubule
D) the collecting ducts
E) the descending limb of the loop of Henle

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The loss of 0.5 L of sweat would stimulate a greater increase in vasopressin secretion than the loss of an equal amount of blood plasma over the same period of time. This statement is:


A) true, because sweat is hyperosmotic to plasma.
B) true, because sweat is hypoosmotic to plasma.
C) false, because sweat is hypoosmotic to plasma.
D) false, because sweat is isosmotic to plasma.
E) false, because sweat is hyperosmotic to plasma.

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Stimuli that cause increased Na+ reabsorption decrease K+ secretion.

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Which of the following symptoms would a patient with a deficiency of parathyroid hormone be most likely to experience?


A) low plasma calcium levels and decreased muscular excitability
B) low plasma calcium levels and increased muscular excitability
C) high plasma calcium levels and decreased muscular excitability
D) high plasma calcium levels and increased muscular excitability
E) high plasma calcium levels and abnormally weak bones

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Both Na+ and Cl- freely filter from the glomerular capillaries into Bowman's space, with no secretion along the renal tubule.

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The anatomic arrangement of juxtamedullary nephrons in the kidneys is such that the glomerulus, proximal tubule, and distal convoluted tubule are in the renal cortex, while the loop of Henle and collecting ducts lie mainly in the renal medulla.

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Which would result from ingesting a large amount of salt?


A) urine osmolarity would decrease
B) atrial natriuretic factor secretion would decrease
C) firing by hypothalamic osmoreceptors would decrease
D) secretion of atrial natriuretic factor would increase
E) secretion of vasopressin would decrease

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Which of the following statements concerning the process of glomerular filtration is correct?


A) The hydrostatic pressure in Bowman's space opposes filtration.
B) The glomerular filtration rate is limited by a transport maximum.
C) All of the plasma that enters the glomerular capillaries is filtered.
D) The osmotic force due to plasma proteins favors filtration.
E) The hydrostatic pressure in glomerular capillaries opposes filtration.

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A

One response to increased H+ production in the body is decreased reabsorption of HCO3- by the kidneys.

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False

After prolonged exertion in a hot climate, baroreceptors would ________ firing, leading to ________ secretion of ________ and thus ________ renal reabsorption of ________.


A) increase; increased; renin; increased; Na+
B) decrease; increased; renin; decreased; Na+
C) decrease; increased; vasopressin; increased; water
D) increase; decreased; vasopressin; decreased; water
E) decrease; decreased; vasopressin; increased; water

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The filtered load of water in an average person is approximately 180 L/day.

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Regulation of extracellular K+ is not critical to body function because only about 2% of the total-body K+ is in the extracellular fluid.

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