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An animal modified by humans to carry genes from another species is called


A) complementary.
B) cloned.
C) antigenic.
D) transgenic.
E) a hybrid species.

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Which of the following is an example of gene therapy?


A) An ear of corn contains genes that produce natural pesticides.
B) A human has one allele for a normal gene and one allele for a mutated gene.
C) A patient with hereditary anemia is given a normal version of the gene.
D) Protein from a healthy person is injected into someone who cannot make that protein.
E) A human protein is made in bacteria for future injection into someone who lacks it.

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Recombinant protein production of spider silk in yeast is an efficient strategy because yeast _____.


A) and spiders are both prokaryotes with similar genes.
B) are easier to house and less expensive to feed than multicellular organisms.
C) are the only organisms that will accept recombinant genes.
D) do not rely on regulatory sequences for genes.
E) do not rely on coding sequences for genes.

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A biologist finds a mutation in a gene,but notices that the protein it encodes is not changed in any way.What kind of mutation could have this effect?


A) insertion of one nucleotide
B) deletion of the start codon
C) deletion of one nucleotide
D) substitution of one nucleotide
E) deletion of the regulatory sequence

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The coding sequence of a gene is the portion of the DNA that


A) determines the timing,amount,and location of the protein produced.
B) acts like an "on/off" switch for gene expression.
C) specifies the shape and function of a protein.
D) encodes for carbohydrates.
E) is removed prior to transcription.

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A gene is a section of a(n) __________ molecule.


A) DNA
B) protein
C) RNA
D) small
E) amino acid

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Translation is the process by which


A) protein is made from amino acids.
B) mRNA is made from a DNA sequence.
C) codons are made from nucleotides.
D) DNA is copied into RNA.
E) All of the above.

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_____amino acids tend to be found folded inside a protein,whereas _____ amino acids interact with water on the outside of the protein.


A) Hydrophilic;hydrophobic
B) Hydrophobic;hydrophilic
C) All;only limited
D) Protein;carbohydrate
E) All;protein

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What does RNA polymerase do?


A) It binds to the regulatory sequence of DNA and produces mRNA.
B) It binds to the coding sequence of RNA and produces proteins.
C) It is an enzyme that binds to and degrades mRNA.
D) It is a protein that binds to DNA and prevents its degradation.
E) It binds to the coding sequence of DNA and prevents it from being expressed.

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A dysfunctional antithrombin protein can result from


A) overexpression of the gene.
B) one allele turning off.
C) DNA replication.
D) a single nucleotide change in the coding region.
E) deep vein thrombosis.

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Use the following information to answer this question: In December 2010,approximately 6000 male mosquitoes were released in Malaysia.They contained a fruit fly gene called "tTA," which kills the mosquito when expressed.In the lab,tTA gene expression was suppressed by treating the mosquitos with tetracycline.The goal for releasing the males was to allow them to mate with wild female mosquitoes.The resulting offspring from this mating would all die,and the number of mosquitoes in the area would plummet,as would the number of humans infected by dengue fever through mosquito bites.The released male mosquitos would then also die from lack of tetracycline-based suppression of tTA gene expression. In the male mosquitoes,tTA is


A) probably fused with a fruit fly regulatory sequence.
B) probably fused with a mosquito regulatory sequence.
C) expressed without a regulatory sequence.
D) a gene normally found in wild populations.
E) an antibiotic that neutralizes the dengue virus.

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Use the following information to answer this question: About 1 in every 100 Caucasians suffers from celiac disease.These individuals have severe allergic responses and digestive problems when they eat certain grains.Their illness is caused specifically by gluten,a protein found in wheat,barley,and rye.Treatments for this disease often rely on dietary supplements that contain protein-degrading enzymes that can break down the gluten during normal digestion,making it harmless. One such enzyme is called AN-PEP (an abbreviation for prolyl endoprotease) ,and it is isolated from the fungus Aspergillus niger.Various research groups are investigating ways to use this enzyme to treat humans.One group is researching the possibility of adding the gene for AN-PEP to wheat so that gluten protein will be detoxified at the very source. The wheat cells manipulated by the research group would probably contain


A) a fungal AN-PEP gene fused to a wheat regulatory sequence.
B) a wheat AN-PEP gene fused to a fungal regulatory sequence.
C) a wheat AN-PEP gene fused to a wheat regulatory sequence.
D) a fungal AN-PEP gene fused to a fungal regulatory sequence.
E) a human AN-PEP gene fused to a wheat regulatory sequence.

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In a spider silk producing transgenic yeast,the _____.


A) spider silk coding sequence is joined with a yeast coding sequence.
B) spider silk regulatory sequence is joined with a yeast coding sequence.
C) spider silk coding sequence is joined with a yeast regulatory sequence.
D) spider silk regulatory sequence is joined with a yeast regulatory sequence.
E) recombinant gene containing small segments of both yeast and spider DNA are expressed in a vector cell.

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An mRNA molecule with 1200 nucleotides from the beginning of the start codon to the end of the stop codon will make a polypeptide that is ____ amino acids long.


A) 400
B) 1200
C) 600
D) 900
E) 399

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All proteins begin with the amino acid


A) glycine (gly) .
B) valine (val) .
C) leucine (leu) .
D) methionine (met) .
E) proline (pro) .

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A piece of mRNA that is 300 bases long can make a protein that has _____ amino acids.


A) 30
B) 100
C) 300
D) 600
E) 900

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What is a transgenic organism?


A) an organism that contains genes from a different species
B) an organism with one or more genes deleted from its genome
C) an organism with one or more of its natural genes mutated by scientists
D) an organism that contains genes from another animal of the same species
E) an organism with two or more genes that have been rearranged between chromosomes

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Antithrombin deficiency can result from


A) a hereditary defect.
B) liver disease.
C) heart disease.
D) kidney disease.
E) All of the above.

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Which statement is FALSE?


A) Thrombosis can be fatal.
B) Antithrombin deficiency is rare.
C) Antithrombin is a protein.
D) Antithrombin prevents blood clots.
E) Antithrombin deficiency can be inherited.

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To get optimal production of a human protein in a spider,scientists fused together


A) human coding sequences and bacteria regulatory sequences.
B) human coding sequences and spider coding sequences.
C) human regulatory sequences and spider regulatory sequences.
D) human regulatory sequences and spider coding sequences.
E) human coding sequences and spider regulatory sequences.

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