Question 1

The 5th Edition of the Diagnostic and Statistical Manual of Mental Disorders classifies substance abuse and substance dependence as:

Accepted Answer

A)   Substance Abuse Disorder.
B)   Substance Use Disorder.
C)   Substance Dependence Disorder.
D)   Substance Diagnostic Disorder.

Question 2

All drugs of abuse affect dopamine levels in the same manner by directly facilitating release from the presynaptic neuron and increasing levels in the synapse.

Accepted Answer

A) True 
 B)False

Question 3

People are thought to develop addictive behaviors because of:

Accepted Answer

A)   a moral failing as a human being.
B)   lower D2 levels.
C)   higher D2 levels.
D)   decreased activity in the dopamine system. B

Question 4

Some evidence suggests that people could be prone to addiction because of:

Accepted Answer

A)   increased dopamine receptor expression.
B)   higher levels of D2 receptors.
C)   higher levels of GABA receptors.
D)   lower levels of D2 receptors.

Question 5

An important change that appears to commonly develop in the brain of chronic drug users is:

Accepted Answer

A)   a higher metabolic rate in the frontal lobe.
B)   a lower metabolic rate in the frontal lobe.
C)   higher firing rate of neurons in the nucleus accumbens.
D)   lower overall activity in the ventral tegmental area (VT
A)  .

Question 6

For patients with a lifetime diagnosis of bipolar disorder,approximately _____ meet the criteria for substance abuse or dependence.

Accepted Answer

A)   25%
B)   50%
C)   75%
D)   90%

Question 7

Downstream neurons connecting frontal lobe structures with the nucleus accumbens (NAc) and the ventral tegmental area (VTA) use _____ as their primary neurotransmitter.

Accepted Answer

A)   dopamine
B)   glutamate
C)   GABA
D)   serotonin

Question 8

Schedule II drugs:

Accepted Answer

A)   have a high potential for abuse.
B)   are not prescribed in the United States.
C)   have a low potential for psychological dependence.
D)   are rarely prescribed outside the United States. A

Question 9

The reward circuit in the brain involves the neurotransmitter:

Accepted Answer

A)   serotonin.
B)   norepinephrine.
C)   acetylcholine.
D)   dopamine.

Question 10

Randy is a chronic cocaine user; he would probably experience less pleasure eating a really excellent meal in comparison to someone that is not a drug user.

Accepted Answer

A) True 
 B)False

Question 11

The key pathway in the brain reward circuit are the neurons connecting the ventral tegmental area with the amygdala.

Accepted Answer

A) True 
 B)False

Question 12

Neuroimaging suggests that when compared to nondrug users,cocaine addicts have a(n) _____ receptors.

Accepted Answer

A)   decreased number of dopamine (D2) 
B)   increased number of dopamine (D2) 
C)   decreased number of GABA
D)   increased number of GABA

Question 13

Recent evidence from the National Survey on Drug Use and Health suggests that drug use is _____ among teenagers and is _____ for individuals in their fifties.

Accepted Answer

A)   moderate; decreasing
B)   lowest; declining
C)   highest; increasing
D)   highest; falling

Question 14

The 5th Edition of the Diagnostic and Statistical Manual of Mental Disorders requires that patients diagnosed with mild substance abuse disorder must:

Accepted Answer

A)   have a comorbid anxiety disorder.
B)   have comorbid depression
C)   exhibit two to three symptoms.
D)   exhibit at least four specific symptoms.

Question 15

Drug use often begins during adolescence.

Accepted Answer

A) True 
 B)False

Question 16

Drug craving is thought to be associated with:

Accepted Answer

A)   increased glutamatergic reactivity.
B)   upregulation of dopamine receptors.
C)   downregulation of GABA receptors.
D)   decreased GABAergic reactivity.

Question 17

In addition to dopamine,serotonin is the other important neurotransmitter that has been shown to be important in the brain reward circuit.

Accepted Answer

A) True 
 B)False

Question 18

Drug addiction is a moral failing on the part of an individual that compulsively uses drugs.

Accepted Answer

A) True 
 B)False

Question 19

Schedule I drugs have no currently accepted medical use in the United States.

Accepted Answer

A) True 
 B)False

Question 20

Nicotine is thought to be addictive because it:

Accepted Answer

A)   enhances influx of calcium into the presynaptic cell.
B)   enhances binding of dopamine at the postsynaptic receptor.
C)   blocks the reuptake / transport of dopamine.
D)   stimulates the release of dopamine. D

Exam 4: Neurobiology of Addiction

The 5th Edition of the Diagnostic and Statistical Manual of Mental Disorders classifies substance abuse and substance dependence as:

Correct AnswerverifiedShow Answer

All drugs of abuse affect dopamine levels in the same manner by directly facilitating release from the presynaptic neuron and increasing levels in the synapse.

Correct AnswerverifiedShow Answer

People are thought to develop addictive behaviors because of:

Correct AnswerverifiedB

Some evidence suggests that people could be prone to addiction because of:

Correct AnswerverifiedShow Answer

An important change that appears to commonly develop in the brain of chronic drug users is:

Correct AnswerverifiedShow Answer

For patients with a lifetime diagnosis of bipolar disorder,approximately _____ meet the criteria for substance abuse or dependence.

Correct AnswerverifiedShow Answer

Downstream neurons connecting frontal lobe structures with the nucleus accumbens (NAc) and the ventral tegmental area (VTA) use _____ as their primary neurotransmitter.

Correct AnswerverifiedShow Answer

Schedule II drugs:

Correct AnswerverifiedA

The reward circuit in the brain involves the neurotransmitter:

Correct AnswerverifiedShow Answer

Randy is a chronic cocaine user; he would probably experience less pleasure eating a really excellent meal in comparison to someone that is not a drug user.

Correct AnswerverifiedShow Answer

The key pathway in the brain reward circuit are the neurons connecting the ventral tegmental area with the amygdala.

Correct AnswerverifiedShow Answer

Neuroimaging suggests that when compared to nondrug users,cocaine addicts have a(n) _____ receptors.

Correct AnswerverifiedShow Answer

Recent evidence from the National Survey on Drug Use and Health suggests that drug use is _____ among teenagers and is _____ for individuals in their fifties.

Correct AnswerverifiedShow Answer

The 5th Edition of the Diagnostic and Statistical Manual of Mental Disorders requires that patients diagnosed with mild substance abuse disorder must:

Correct AnswerverifiedShow Answer

Drug use often begins during adolescence.

Correct AnswerverifiedShow Answer

Drug craving is thought to be associated with:

Correct AnswerverifiedShow Answer

In addition to dopamine,serotonin is the other important neurotransmitter that has been shown to be important in the brain reward circuit.

Correct AnswerverifiedShow Answer

Drug addiction is a moral failing on the part of an individual that compulsively uses drugs.

Correct AnswerverifiedShow Answer

Schedule I drugs have no currently accepted medical use in the United States.

Correct AnswerverifiedShow Answer

Nicotine is thought to be addictive because it:

Correct AnswerverifiedD

The 5^th Edition of the Diagnostic and Statistical Manual of Mental Disorders classifies substance abuse and substance dependence as:

Correct Answer
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B

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A

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Recent evidence from the National Survey on Drug Use and Health suggests that drug use is _ among teenagers and is _ for individuals in their fifties.

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The 5^th Edition of the Diagnostic and Statistical Manual of Mental Disorders requires that patients diagnosed with mild substance abuse disorder must:

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D