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The "first-pass effect" refers to drug metabolism in the liver.

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Which of the following is not an advantage of the oral route of drug administration?


A) it is safe
B) it has the quickest rate of absorption
C) it is convenient
D) it is economical

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Drugs that are more soluble in lipids (fats) are less readily absorbed than other drugs.

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The elimination of a drug from the body often is associated with changes that are opposite to those that were caused by the drug. These are sometimes called .


A) flashbacks
B) rebound effects
C) delirium tremens
D) withdrawal symptoms

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Which of the following affect drug distribution?


A) blood flow
B) fat solubility of the drug
C) diffusibility of membranes
D) all of these
E) blood flow and diffusibility of membranes only

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D

Recent research has indicated that environmental differences do not seem to play a role in the pharmacokinetics of drug metabolism.

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In a prototypic dose-effect curve, the vertical axis refers to the and the horizontal axis refers to the __________.


A) range of drug doses, effect size
B) effect size, number of drugs
C) number of drugs, effect size
D) effect size, range of drug doses

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The process by which the body breaks down matter into more simple components and waste is known as ____________.


A) absorption
B) metabolism
C) synthesis
D) biotransformation

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Drinking large quantities of water would be an example of an attempt to alter the results of a drug test by _________.


A) dilution
B) adulteration
C) substitution
D) none of these

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Describe the processes involved in drug absorption, distribution, and elimination. What major organs are involved in these processes?

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Answered by ExamLex AI

Drug absorption, distribution, and elimi...

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Drug potency refers to the largest amount of a drug than can be taken safely.

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How many poppy seed bagels would need to be consumed in order to obtain a positive screen for opiates?


A) 2
B) 10
C) 25
D) 100

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reflects the amount of latitude there is in a drug dose before a stronger effect is reached.


A) Slope
B) Potency
C) Effective dose
D) Synergism

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When drugs are swallowed, they pass through the stomach and are absorbed in the .


A) small intestine
B) kidneys
C) liver
D) large intestine

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In research, means to be able to account for variables that may affect the results of a study.


A) independence
B) blindness
C) control
D) none of these

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C

Which of the following conditions lead to more rapid drug absorption?


A) when there is more blood flow at the site of absorption
B) when the absorbing surface is smaller
C) when drugs are taken in suspension, rather than aqueous solution
D) all of these

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Which of the following is an example of an inhalant?


A) nitroglycerin
B) cocaine
C) benzene
D) snuff

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Why is awareness of drug interactions important? What is the difference between the qualitative and quantitative drug interaction effects?

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Awareness of drug interactions is crucial because it helps to ensure the safety and effectiveness of medications. Drug interactions can occur when one drug affects the activity of another when both are administered together. These interactions can lead to unexpected side effects, reduce or enhance the effectiveness of one or both drugs, or increase the risk of adverse reactions. Understanding these interactions is important for healthcare providers when prescribing medications and for patients to avoid potential health risks. There are two main types of drug interaction effects: qualitative and quantitative. Qualitative drug interactions refer to changes in the type of effect that a drug has when combined with another substance. This could mean that a new effect is produced that neither drug would cause on its own, or that one drug alters the characteristic effect of the other. For example, when alcohol is consumed with sedative medications, it can produce a new effect of significantly increased sedation or respiratory depression, which neither substance might cause to such a degree on its own. Quantitative drug interactions, on the other hand, refer to changes in the magnitude or intensity of the effect of a drug. This can be an increase (potentiation) or a decrease (inhibition) in the expected pharmacological action. For instance, if Drug A inhibits the metabolism of Drug B, the levels of Drug B may increase in the bloodstream, leading to an enhanced effect or potential toxicity. Conversely, if Drug A induces the metabolism of Drug B, the levels of Drug B may decrease, reducing its efficacy. Both qualitative and quantitative drug interactions can have significant clinical implications. Awareness and understanding of these interactions allow healthcare professionals to predict potential risks and manage them proactively by adjusting dosages, timing of administration, or choosing alternative medications that do not interact. For patients, being informed about possible drug interactions can help them to communicate effectively with their healthcare providers and to use medications safely.

Which of the following is a common site for intramuscular drug injection?


A) buttocks
B) deltoid
C) thigh
D) all of these
E) buttocks or deltoid only

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A drug is when it changes from solid to liquid after being mixed with a liquid.


A) dissolved
B) suspended
C) diffused
D) absorbed

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