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You are researching a cytoplasmic protein associated with a nerve disorder.The native form of the enzyme appears to be globular protein; however,when a sample of the purified protein is treated with a chemical that reduces disulfide bonds,the enzymatic activity decreases dramatically and multiple globular proteins can be detected in the sample.What does this tell you about the protein?


A) The primary structure of the protein contains multiple cysteine residues that are hydrolyzed by the chemical reductant.
B) The protein is most likely composed of multiple polypeptide chains that are held together by disulfide bonds.
C) The protein is most likely composed of α helices that are held together by disulfide bonds.
D) The protein is most likely composed of β sheets that are held together by disulfide bonds.
E) The primary and secondary structure of the protein depends on disulfide bonds.

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Disulfide bonds are often found to stabilize which of the following levels of protein structure?


A) primary
B) secondary
C) tertiary
D) primary,secondary,and tertiary
E) None of these structures involve disulfide bonds.

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C

The components of a nucleotide are


A) a carboxyl group,an amine group,and a variable R group.
B) a five-carbon sugar,a phosphate group,and a nitrogen-containing aromatic base.
C) a three-carbon alcohol with a hydroxyl group on each carbon and three fatty acids.
D) two six-carbon sugars attached with an α(1→4) glycosidic bond.
E) a six-carbon sugar,an ester linkage,and a four-ringed hydrocarbon.

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Which of the following is true of glycolipids?


A) Glycolipids are usually found on the exterior surface of the plasma membrane.
B) Glycolipids are found in plastids and are used to store energy.
C) Fructose and sucrose are often part of glycolipids.
D) Glycolipids contain steroids.
E) Usually more than 10 sugar units are attached to the glycolipid.

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Two proteins associated with a rare neurodegenerative disorder have been sequenced.Protein A contains many polar amino acids with small regions containing nonpolar,hydrophobic amino acids.Protein B is rich in nonpolar,hydrophobic amino acids with only two small regions containing polar amino acids.What might this suggest about the two proteins?


A) The two proteins may have different secondary structures.
B) Protein A is fibrous and Protein B is globular.
C) Protein A may be a cytoplasmic protein and Protein B may be a membrane associate protein.
D) Protein A and Protein B are complementary parts of a supramolecular structure.
E) Protein A is most likely and enzyme and Protein B is most likely a storage protein.

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Give an example of both fibrous and globular proteins and explain how their structure relates to their unique functions.

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Fibrous proteins such as (silk,collagen,...

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The nucleoside triphosphate molecules in DNA are linked together in the 5'→3' by a(n) ________ bridge.


A) phosphate
B) covalent
C) phosphodiester
D) peptide
E) phosphatidyl

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Proline is referred to as the "helix breaker" because


A) its only found in the L form,which is incompatible with helical protein structure.
B) it lacks the hydrogen atom needed for hydrogen bonding.
C) it lacks a charged functional groups for ionic bonding.
D) it is hydrophobic.
E) it has a polar functional group.

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________ RNA is a component of the ribosomes that serve as the site of protein synthesis.

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Which of the following is a terpene?


A) testosterone
B) vitamin A
C) glycerol
D) estrogen
E) chitin

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B

A transmembrane protein has 1000 amino acids.The fifth amino acid is found on the external surface of the cell membrane.It interacts with the aqueous environment outside the cell.Amino acids 25 and 205 are covalently bonded to each other and are required to give the protein its three-dimensional shape.Amino acid 554 is found on the outer surface of the protein,but it is deep in the interior of the membrane.Amino acid 979 is found on the external surface of the protein,where it forms a weak ionic bond with a chloride ion.Can you identify each of the numbered amino acids by structural group and name? Please note that there may be more than one specific amino acid possible in some cases. Amino acids: 5 25 205 554 979

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5: polar,charged or uncharged (hydrophil...

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Which of the following is found exclusively in RNA?


A) thymine
B) guanine
C) uracil
D) adenine
E) cytosine

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Which of the following is not a major functional class of proteins?


A) hereditary proteins
B) enzymes
C) motility proteins
D) regulatory proteins
E) structural proteins

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A

Amylose,cellulose,and glycogen are all polysaccharides composed of glucose.What makes each of these polysaccharides unique in spite of the fact that all are composed solely of glucose?

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Amylose: is produced by plants and is a ...

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Which of the following is not a polymer of numerous monomer units?


A) a phospholipid
B) a polypeptide
C) an RNA molecule
D) cellulose
E) starch

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Which of the following is not a steroid?


A) testosterone
B) estradiol
C) cortisol
D) aldosterone
E) phenylalanine

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The chemical nature of each amino acid is determined by which of the following groups?


A) amino
B) carboxyl
C) hydroxyl
D) R
E) hydrogen

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Which of the following is not one of the six classes of lipids?


A) steroids
B) terpenes
C) fatty acids
D) triacylglycerols
E) pectins

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For the amino acid glutamine,the three-letter abbreviation is ________ and the one-letter abbreviation is ________.

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Which of the following accurately describes the structure of fibrous proteins?


A) Fibrous proteins usually contain a number of different domains with different structural motifs.
B) Fibrous proteins are composed of an equal mixture of α helices and β sheets with interconnecting looped segments.
C) Fibrous proteins have an extensive tertiary and quaternary structure that affects the strength and elasticity of each fiber.
D) Fibrous proteins have a simple primary structure and very little secondary structure,resulting in long,thin fibers.
E) Fibrous proteins are usually composed of either α helices or β sheets throughout the molecule,giving them a highly ordered,repetitive structure.

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