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Atropine, first derived from the Atropa belladonna plant, is a nicotinic receptor antagonist.

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Norepinephrine is one of the more important neurotransmitters of the peripheral nervous system. Identify the branches of the peripheral nervous system for which norepinephrine is the neurotransmitter and describe the receptors responsible for responding to norepinephrine. Include the mechanisms whereby these receptors transduce the response to norepinephrine.

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Neurons that release norepinephrine are ...

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Which of the following contributes to the ability of the sympathetic nervous system to produce widespread responses within the body?


A) Several preganglionic neurons activate a single postganglionic neuron.
B) One preganglionic neuron sends collaterals to multiple ganglia, affecting multiple postganglionic neurons.
C) Multiple preganglionic neurons innervate each ganglion, sending out individual postganglionic neurons.
D) One preganglionic neuron can activate only one postganglionic neuron.
E) One postganglionic neuron branches into many collaterals that affect multiple organs.

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Which of the following is indicative of the relative release of catecholamines from the adrenal medulla?


A) 80% epinephrine : 20% dopamine
B) 100% acetylcholine
C) 80% norepinephrine : 20% dopamine
D) 80% norepinephrine : 20% epinephrine
E) 80% epinephrine : 20% norepinephrine

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What enzyme degrades the neurotransmitter released from varicosities of parasympathetic postganglionic neurons?


A) choline acetyl transferase
B) catechol -O -methyltransferase only
C) monoamine oxidase only
D) catechol -O -methyltransferase and monoamine oxidase
E) acetylcholinesterase

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The autonomic nervous system consists of efferent pathways with two peripheral neurons that travel in series from the central nervous system to the effector organ.

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Postganglionic neurons of the autonomic nervous system release neurotransmitter from


A) dendrites.
B) varicosities.
C) axon hillock.
D) somas.
E) neuromuscular junction.

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Students who suffer from test anxiety often have some of the following symptoms: the need for frequent urination, dilated pupils, and a dry mouth. What branch of the autonomic nervous system would cause these symptoms?


A) somatic
B) enteric
C) voluntary
D) parasympathetic
E) sympathetic

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At rest, what is the relative contribution of the sympathetic and parasympathetic nervous systems to the regulation of homeostasis?


A) Only the parasympathetic system is active.
B) Only the sympathetic system is active.
C) Both systems are active but the parasympathetic predominates.
D) Both systems are active but the sympathetic predominates.
E) Neither system is active.

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The opening of a cation channel that allows both Na+ and K+ to move through will cause the membrane to because of the _.


A) depolarize : greater K+ electrochemical gradient as compared with Na+
B) hyperpolarize : greater K+ electrochemical gradient as compared with Na+
C) depolarize : greater Na+ electrochemical gradient as compared with K+
D) not change : same electrochemical gradient for K+ and Na+
E) hyperpolarize : greater Na+ electrochemical gradient as compared with K+

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What is the graded change in membrane potential that occurs at the motor end plate of skeletal muscle called?


A) action potential
B) adrenergic potential
C) end -plate potential
D) muscarinic potential
E) inhibitory postsynaptic potential

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Describe the synaptic junctions between the neurons of the autonomic and somatic nervous systems and their effector organs.

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The neuroeffector junction describes the...

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Neurons that release norepinephrine are referred to as adrenergic.

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What area of the brain initiates the fight -or -flight response by producing widespread activation of the sympathetic nervous system?


A) cerebellum
B) hypothalamus
C) brainstem
D) amygdala
E) limbic system

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The nature of a response from the parasympathetic nervous system is determined by the anatomy of this system. Describe the anatomy of the parasympathetic nervous system and how that differs from the sympathetic nervous system.

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Preganglionic neurons from the parasympa...

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Where do the preganglionic neurons of the sympathetic nervous system emerge from the spinal cord?


A) lumbar region only
B) thoracic and lumbar regions
C) sacral region only
D) thoracic region only
E) lumbar and sacral regions

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Test anxiety involves worry and dread about test performance and often interferes with normal learning and lowers test performance. 20 -30% of American students have experienced test anxiety. Some causes of test anxiety include fear of failure, waiting until the last minute to study, and/or those who have had trouble taking tests in the past. List at least five symptoms of test anxiety. Explain what autonomic division are the cause of the symptoms and its effect on target organs. Finally, what drug might be prescribed to alleviate the symptoms of text anxiety and explain its mode of action?

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During states of excitement or stress yo...

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The primary hormone released from the adrenal medulla is norepinephrine.

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Which of the following statements is TRUE of communication across the neuromuscular junction?


A) Synaptic communication to the muscle cell can be excitatory or inhibitory.
B) Acetylcholine released from a motor neuron binds to muscarinic cholinergic receptors.
C) Acetylcholinesterase located in mitochondria of the motor neuron degrades acetylcholine to acetate and choline.
D) The end -plate potential is always of sufficient magnitude to depolarize the muscle cell to threshold to initiate an action potential.
E) Acetylcholinesterase located in the cytosol of the motor neuron degrades acetylcholine to acetate and choline.

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What is the correct order for the steps of synaptic transmission at the motor end plate? 1. Acetylcholine binds to postsynaptic receptors. 2) Acetylcholine is released by exocytosis. 3) A graded depolarization is produced. 4) An action potential is produced on the muscle cell membrane. 5) Channels that primarily allow diffusion of sodium are opened. 6) Voltage -dependent calcium channels on the plasma membrane open. 7) An action potential arrives at the axon terminal.


A) 5, 7, 6, 2, 1, 4, 3
B) 7, 6, 2, 1, 3, 4, 6
C) 6, 7, 2, 1, 3, 5, 4
D) 7, 5, 2, 1, 3, 4, 6
E) 7, 6, 2, 1, 5, 3, 4

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