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The mutagens 2- aminopurine and 5- bromouracil are examples of


A) alkylating agents.
B) chemicals reacting with DNA.
C) nucleotide base analogs.
D) none of the above.

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Name and describe a test that could be performed to determine if a kitchen chemical cleaner is mutagenic. Also mention the purpose of control(s) for the test and how the results are interpreted.

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The Ames test could be used to determine...

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The SOS regulatory system is activated by


A) transcription of LexA.
B) repression of RecA.
C) DNA damage.
D) the activity of DNA polymerase IV.

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________when a bacterium's phenotype changes as the result of a(n)________ into its genome.

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Phage conv...

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The minimal amount of genetic information required for specialized transduction would include


A) the cos site.
B) a helper phage.
C) the att region.
D) all of the above.

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Genetic recombination involving insertion sequences typically results in what type of mutation?


A) missense mutation
B) frameshift mutation
C) silent mutation
D) base- pair substitution mutation

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Following uptake, transforming DNA becomes attached to a competence- specific protein that prevents it from nuclease attack until it reaches the chromosome.

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________is a specific type of transformation where bacteriophage DNA is taken up by bacterial cells.

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Frederick Griffith's experiments, which showed that the R strain was able to pick up DNA from a heat- treated S strain of Streptococcus pneumonia, provided the first evidence of


A) homologous recombination.
B) transformation.
C) transduction.
D) conjugation.

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Consider a mutation in which the change is from UAC to UAU. Both codons specify the amino acid tyrosine. Which type of point mutation is this?


A) frameshift mutation
B) missense mutation
C) silent mutation
D) nonsense mutation

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All Hfr strains possess an F factor integrated into the host chromosome.

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Hfr means________ , and these cells are capable of transferring genes from their ________.

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high frequ...

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ISs do not encode for known phenotypic traits and are smaller than either Tn or Mu.

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Explain why point mutations may occasionally revert, while large- scale deletions do not revert.

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Because a point mutation involves only a...

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Which process involves the formation of Holliday junctions?


A) transformation
B) transduction
C) homologous recombination
D) conjugation

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The F (fertility) plasmid contains a set of genes that encode for the________ proteins that are essential in conjugative transfer of DNA.

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A strain of an organism with an increased mutation rate is known as a(n)


A) encoded dnaQ system.
B) adaptive mutagen strain.
C) phenotypic variation.
D) hypermutable or mutator strain.

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The designations Phe- , Leu- , and Ser+ refer to an organism's _________.

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The evolutionary significance of phage conversion likely stems from an effective alteration of host cells.

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Penicillin selection is a positive selection for the isolation of mutants with growth factor requirements.

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