Question 1

piRNA sequences are complimentary to

Accepted Answer

A)   mRNA from a transposable element.
B)   another RNA within the piRISC.
C)   the Crispr gene.
D)   bacteriophage DNA.

Question 2

A bacterial ncRNA called OxyS regulates translation by binding to the Shine-Dalgarno sequence, which prevents ribosome binding. What is the function of this ncRNA?

Accepted Answer

A)   Blocker
B)   Decoy
C)   Ribozyme
D)   Scaffold

Question 3

What is the make up of the bacterial and eukaryotic SRP, respectively?

Accepted Answer

A)   Bacterial: 1 ncRNA, 1 protein; Eukaryotic: 1 ncRNA, 6 proteins
B)   Bacterial: 1 ncRNA, 1 protein; Eukaryotic: 6 ncRNAs, 1 protein
C)   Bacterial: 1 ncRNA, 6 proteins; Eukaryotic: 1 ncRNA, 6 proteins
D)   Bacterial: 6 ncRNAs, 1 protein; Eukaryotic: 1 ncRNA, 1 protein

Question 4

An RNA molecule with catalytic activity is called a(n)

Accepted Answer

A)   ribozyme.
B)   ncRNA.
C)   snRNA
D)   miRNA.

Question 5

What ability, which modern eukaryotic cells also possess, did cells in an RNA world probably acquire that explains the existence of DNA?

Accepted Answer

A)   Reverse transcription
B)   DNA replication
C)   Translation
D)   RNA splicing

Question 6

Based on what you know about cartilage-hair hypoplasia, which strategy involving ncRNAs do you anticipate would be useful in treating this disease?

Accepted Answer

A)   A viral vector to restore a particular miRNA
B)   Anti-miRNA oligonucleotides
C)   Targeting of the miRNA-processing machinery
D)   Use of DNA demethylating agents and histone deacetylase inhibitors

Question 7

Consider the two key roles that have been identified for SRP RNA. You have isolated a mutant SRP RNA. This RNA is able to perform its role as a scaffold for SRP proteins, but has lost its other function. How will this affect translation of SRP-containing proteins?

Accepted Answer

A)   Partially translated proteins will be stuck in the cytosol.
B)   Partially translated proteins will be stuck in the ER lumen.
C)   Partially translated proteins will be stuck in the nucleus.
D)   Translation will proceed normally.

Exam 17: Non-Coding Rnas

Based on what you know about cartilage-hair hypoplasia, which strategy involving ncRNAs do you anticipate would be useful in treating this disease?

Correct Answer
verified

What ability, which modern eukaryotic cells also possess, did cells in an RNA world probably acquire that explains the existence of DNA?

Correct Answer
verified

piRNA sequences are complimentary to

Correct Answer
verified

An RNA molecule with catalytic activity is called a(n)

Correct Answer
verified

What is the make up of the bacterial and eukaryotic SRP, respectively?

Correct Answer
verified

A bacterial ncRNA called OxyS regulates translation by binding to the Shine-Dalgarno sequence, which prevents ribosome binding. What is the function of this ncRNA?

Correct Answer
verified

Consider the two key roles that have been identified for SRP RNA. You have isolated a mutant SRP RNA. This RNA is able to perform its role as a scaffold for SRP proteins, but has lost its other function. How will this affect translation of SRP-containing proteins?

Correct Answer
verified

Exam 17: Non-Coding Rnas

Based on what you know about cartilage-hair hypoplasia, which strategy involving ncRNAs do you anticipate would be useful in treating this disease?

Correct AnswerverifiedShow Answer

What ability, which modern eukaryotic cells also possess, did cells in an RNA world probably acquire that explains the existence of DNA?

Correct AnswerverifiedShow Answer

piRNA sequences are complimentary to

Correct AnswerverifiedShow Answer

An RNA molecule with catalytic activity is called a(n)

Correct AnswerverifiedShow Answer

What is the make up of the bacterial and eukaryotic SRP, respectively?

Correct AnswerverifiedShow Answer

A bacterial ncRNA called OxyS regulates translation by binding to the Shine-Dalgarno sequence, which prevents ribosome binding. What is the function of this ncRNA?

Correct AnswerverifiedShow Answer

Consider the two key roles that have been identified for SRP RNA. You have isolated a mutant SRP RNA. This RNA is able to perform its role as a scaffold for SRP proteins, but has lost its other function. How will this affect translation of SRP-containing proteins?

Correct AnswerverifiedShow Answer

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified