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Exam 3: Amino Acids and Peptides

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Question 1

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What is the predominant form of the amino acid abbreviated val at pH 7?

A) positive
B) neutral
C) negative

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B

Question 2

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$\begin{array}{l}\text { Exhibit } \mathbf { 3 A } \text { (for this chapter) }\\\begin{array} { l l l l } \text { Amino acid } & \boldsymbol { \alpha } \text {-carboxyl group pK a } & \boldsymbol { \alpha } \text {-amino group pK a } & \text { R-group pK } \\\hline \text { Ala } & 2.3 & 9.7 & \\\text { Arg } & 2.2 & 9.0 & 12.5 \\\text { Asn or Gln } & 2.1 & 9.0 & 4.0 \\\text { Asp or Glu } & 2.2 & 9.8 & 8.3 \\\text { Cys } & 1.7 & 10.8 & 6.0 \\\text { His } & 1.8 & 9.2 & \\\text { Ser } & 2.2 & 9.2 & 10.1\end{array}\end{array}$ -Refer to Exhibit 3A. Which one has the R-group with the highest pK?

A) Alanine
B) Arginine
C) Histidine
D) Cysteine
E) Aspartic Acid

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Question 3

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How many possible tetrapeptides can be made using all four of the amino acids D, W, F, and R?

The side chain groups of amino acids are bonded to which carbon?

$\begin{array}{l}\text { Exhibit } \mathbf { 3 A } \text { (for this chapter) }\\\begin{array} { l l l l } \text { Amino acid } & \boldsymbol { \alpha } \text {-carboxyl group pK a } & \boldsymbol { \alpha } \text {-amino group pK a } & \text { R-group pK } \\\hline \text { Ala } & 2.3 & 9.7 & \\\text { Arg } & 2.2 & 9.0 & 12.5 \\\text { Asn or Gln } & 2.1 & 9.0 & 4.0 \\\text { Asp or Glu } & 2.2 & 9.8 & 8.3 \\\text { Cys } & 1.7 & 10.8 & 6.0 \\\text { His } & 1.8 & 9.2 & \\\text { Ser } & 2.2 & 9.2 & 10.1\end{array}\end{array}$ -Refer to Exhibit 3A. Calculate the pI of ASN:

Which amino acid has a polar, non-ionic R-group

Which group consists only of amino acids with polar side chains?

Which of the following correctly describes peptide bonds?

The isoelectric pH of glycine is closest to

Which amino acid has the one-letter symbol E?

Which statement is true about the classification of amino acids?

$\begin{array}{l}\text { Exhibit } \mathbf { 3 A } \text { (for this chapter) }\\\begin{array} { l l l l } \text { Amino acid } & \boldsymbol { \alpha } \text {-carboxyl group pK a } & \boldsymbol { \alpha } \text {-amino group pK a } & \text { R-group pK } \\\hline \text { Ala } & 2.3 & 9.7 & \\\text { Arg } & 2.2 & 9.0 & 12.5 \\\text { Asn or Gln } & 2.1 & 9.0 & 4.0 \\\text { Asp or Glu } & 2.2 & 9.8 & 8.3 \\\text { Cys } & 1.7 & 10.8 & 6.0 \\\text { His } & 1.8 & 9.2 & \\\text { Ser } & 2.2 & 9.2 & 10.1\end{array}\end{array}$ -Refer to Exhibit 3A. The pI of an amino acid is the pH at which it has a zero net charge. What is the increasing order of isoelectric points (low pH to high) for these three amino acids?

The pK_a values of the amino groups of common amino acids

Which of the following is NOT a correct combination of an amino acid, its three-letter designation, and its one-letter designation?

Exhibit 3B A titration curve. -Refer to Exhibit 3B. The amino acid depicted by the titration curve is

Which is the correct one-letter designation for tryptophan?

What is the predominant form of the amino acid abbreviated E at pH 7?

At its isolectric pH, glycine will have

Which of the following is true about oxytocin?

Which amino acid would likely be least water-soluble at pH 7.0