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A person on a high-protein diet will have high levels of protein in their urine.

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Which of the following most accurately describes the renal transport of Na⁺?


A) Na⁺ is actively transported in all segments of the tubule.
B) Primary active transport of Na⁺ allows for secondary active transport of glucose and H⁺ in the proximal tubule.
C) Most of the Na⁺ transport occurs in the distal convoluted tubule and collecting ducts.
D) Na⁺ is actively secreted into the nephron lumen by cells in the cortical collecting ducts.
E) Na⁺ is actively transported across the luminal membrane of proximal tubule cells in exchange for K⁺,by Na⁺/K⁺ ATPase pumps.

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Which of the following does NOT correctly describe kidney function?


A) They contribute significantly to long-term regulation of arterial blood pressure by maintaining the proper plasma volume.
B) They produce urine of a constant composition at all times,in order to maintain homeostasis of extracellular fluid.
C) They excrete metabolic waste products.
D) They assist in maintaining proper acid-base balance in the body.
E) They secrete hormones.

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You are designing a urinalysis test to be used in doctors' offices.You want the test to be able to indicate a variety of problems with kidney function,but you want the test to be as simple and inexpensive as possible.Testing for the presence of which of the following in the urine would indicate a potential problem with kidney function? 


A) Protein
B) H⁺
C) K⁺
D) Na⁺
E) Glucose

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Stimuli that cause increased Na⁺ reabsorption decrease K⁺ secretion.

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Water,sodium,and glucose all undergo tubular reabsorption,but urea does not.

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A stimulus for increased aldosterone secretion is increased plasma levels of K⁺.

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If damage to the glomerular capillaries resulted in significantly enlarged filtration slits in the endothelial lining,one consequence might be loss of protein in the urine.

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People taking diuretics that do not spare K⁺ should increase their ingestion of Na⁺.

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Most of the H⁺ excreted in the urine is bound to bicarbonate ion.

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A misguided athlete ingests a large amount of dietary K+ because she thinks it will boost muscle performance.Instead,the majority of this extra K+ is secreted into filtrate and excreted in the urine.

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The anatomic arrangement of juxtamedullary nephrons in the kidneys is such that the glomerulus,proximal tubule,and distal convoluted tubule are in the renal cortex,while the loop of Henle and collecting ducts lie mainly in the renal medulla.

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In the proximal convoluted tubule the reabsorption of Na⁺ is unaffected by the presence or absence of other substances such as glucose or H⁺ in the filtrate.

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A patient receives an IV (intravenous)infusion of a concentrated,9% saline solution (0.9% is considered isosmotic).Even if there was no change to the volume of blood or water in the body,this patient is likely to experience extreme thirst following the infusion.

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Jerome has had too many alcoholic drinks at a party.One of the effects of alcohol is that it inhibits the release of vasopressin.Which of the following is Jerome likely to notice?


A) A reduction in urine volume
B) The excretion of glucose in the urine increased
C) High volume of dilute urine
D) Very concentrated urine
E) An increase in blood pressure

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Which of the following statements regarding renal handling of Na⁺ is correct?


A) In the proximal tubule,Na⁺ is actively transported across the luminal membrane of the tubular epithelial cells.
B) Atrial natriuretic factor increases Na⁺ reabsorption.
C) In the absence of aldosterone,Na⁺ will be secreted by the cortical collecting ducts.
D) Na⁺ is actively reabsorbed in the ascending limb of the loop of Henle.
E) Without vasopressin,the collecting duct is impermeable to Na⁺.

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In a person with respiratory acidosis,HCO₃⁻ is actively secreted into the urine by the tubular cells.

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Following an intense workout your clothes are drenched in sweat.You estimate you lost at least 0.5 L of sweat.Your (similarly sized) friend skipped her workout to donate blood and you found out she donated 0.5 L of plasma.After these activities,which of you will have a greater increase in vasopressin secretion and why? 


A) You will have a greater vasopressin secretion because sweat is hyperosmotic to plasma.
B) You will have a greater vasopressin secretion because sweat is hypoosmotic to plasma.
C) Your friend will have a greater vasopressin secretion because sweat is hypoosmotic to plasma.
D) Your friend will have a greater vasopressin secretion because sweat is isosmotic to plasma.
E) Your friend will have a greater vasopressin secretion because sweat is hyperosmotic to plasma.

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The walls of the ascending limb of the loop of Henle are freely permeable to water.

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Which is NOT a transport mechanism typically seen in renal tubular epithelial cells?


A) Cotransport proteins in the luminal membrane of the proximal tubule that move Na⁺ and glucose from the proximal tubule into epithelial cells
B) Transport proteins that move glucose by facilitated diffusion from inside of proximal tubule cells into the renal interstitial fluid
C) Ion channels that allow Na⁺ to move by diffusion from the lumen of the proximal tubule into epithelial cells
D) Na⁺-K⁺ ATPase pumps in the luminal membrane of proximal tubule epithelial cells that move Na⁺ from inside the cell into the tubule and K⁺ from the tubule lumen into the cell 
E) Countertransport proteins that move Na⁺ into proximal tubule epithelial cells while moving H⁺ from the cells into the lumen 

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