Question 1

What type of inheritance is observed with extranuclear DNA?

Accepted Answer

A)  Mendelian inheritance
B)  Sex-linked inheritance
C)  Paternal inheritance
D)  Maternal inheritance
E)   Maternal effect

Question 2

Which of the following is false regarding mtDNA?

Accepted Answer

A)   It is around 17,000 bp in length
B)   It is a linear chromosome
C)   Multiple copies exist in each mitochondria
D)   It mostly contains rRNA and tRNA genes

Question 3

Where is extranuclear DNA located in mammalian cells?

Accepted Answer

A)  Endoplasmic reticulum
B)  Mitochondria
C)  Ribosome
D)  Plasma membrane

Question 4

How many Barr bodies would an individual with a XXY genotype possess?

Accepted Answer

A)  0
B)  1
C)  2
D)  None of the answers are correct

Question 5

What gene is most responsible for X-inactivation?

Accepted Answer

A)  Xic
B)  Xist
C)  Tsix
D)  Xce

Question 6

In which cells do erasure and re-establishment of imprinting marks typically NOT occur?

Accepted Answer

A)  Nurse cells
B)  Sperm cells
C)  Oocytes
D)  Somatic cells

Question 7

The inheritance patterns of genetic material that is not contained in the nucleus of the cell is called _______.

Accepted Answer

A)  extranuclear inheritance
B)  maternal effect
C)  imprinting
D)  nuclear
E)  epigenetic

Question 8

Dosage compensation offsets the problems associated with differences in the number of _______ chromosomes in many species.

Accepted Answer

A)   cytoplasmic
B)   autosome
C)   sex
D)   extranuclear
E)   mitochondrial

Question 9

What is the molecular mechanism for imprinting a gene?

Accepted Answer

A)  Acetylation
B)  Nitration
C)  Phosphorylation
D)  Methylation

Question 10

What is a disease associated with extra nuclear inheritance?

Accepted Answer

A)  Angelman Syndrome
B)  Prader-Willi Syndrome
C)  LHON
D)  Muscular Dystrophy C

Question 11

mtDNA stands for _______ and cpDNA stands for _______.

Accepted Answer

A)   extranuclear DNA, cytoplasmic DNA
B)   maternal DNA, paternal DNA
C)   marked DNA, copied DNA
D)   nuclear, cytoplasmic
E)   mitochondrial DNA, chloroplast DNA

Question 12

What encodes the toxin paramecin in Paramecia aurelia?

Accepted Answer

A)  mtDNA
B)  cpDNA
C)  Nuclear DNA
D)  Kappa particles

Question 13

What genes appear to be controlled by the Xic?

Accepted Answer

A)  Xist and Tsix
B)  Xist only
C)  Tsix only
D)  None of these

Question 14

Which of the following is primarily responsible for the maternal effect?

Accepted Answer

A)  Sperm cells
B)  Oocytes
C)  Nurse cells
D)  Placenta

Question 15

Most imprinted genes are silenced. What is one exception to this rule?

Accepted Answer

A)  H19
B)  Igf2
C)  UBE3A
D)  SNRPN

Question 16

In the gene that affects snail coiling, the ______ is responsible for the phenotype of the offspring.

Accepted Answer

A)   mother's phenotype
B)   father's phenotype
C)   mother's genotype
D)   father's genotype C

Question 17

Which diseases are associated with imprinting?

Accepted Answer

A)  Angelman Syndrome
B)  LHON
C)  Alzheimer's Disease
D)  All of the answers are correct

Question 18

In the Igf2 gene, which allele is imprinted? Which is expressed?

Accepted Answer

A)  Paternal, paternal
B)  Paternal, maternal
C)  Maternal, paternal
D)  Maternal, maternal

Question 19

If the sperm cell contributes mitochondria to the oocyte, it is called _______.

Accepted Answer

A)   paternal leakage
B)   maternal leakage
C)   paternal inheritance
D)   mitochondria
E)   imprinting A

Question 20

Heteroplasmy is associated with inheritance patterns involving

Accepted Answer

A)   nuclear.
B)   paternal DNA.
C)   chloroplasts.
D)   ribosomes.
E)   imprinted.

Exam 5: Non-Mendelian Inheritance

What type of inheritance is observed with extranuclear DNA?

Correct AnswerverifiedShow Answer

Which of the following is false regarding mtDNA?

Correct AnswerverifiedShow Answer

Where is extranuclear DNA located in mammalian cells?

Correct AnswerverifiedShow Answer

How many Barr bodies would an individual with a XXY genotype possess?

Correct AnswerverifiedShow Answer

What gene is most responsible for X-inactivation?

Correct AnswerverifiedShow Answer

In which cells do erasure and re-establishment of imprinting marks typically NOT occur?

Correct AnswerverifiedShow Answer

The inheritance patterns of genetic material that is not contained in the nucleus of the cell is called _______.

Correct AnswerverifiedShow Answer

Dosage compensation offsets the problems associated with differences in the number of _______ chromosomes in many species.

Correct AnswerverifiedShow Answer

What is the molecular mechanism for imprinting a gene?

Correct AnswerverifiedShow Answer

What is a disease associated with extra nuclear inheritance?

Correct AnswerverifiedC

mtDNA stands for _______ and cpDNA stands for _______.

Correct AnswerverifiedShow Answer

What encodes the toxin paramecin in Paramecia aurelia?

Correct AnswerverifiedShow Answer

What genes appear to be controlled by the Xic?

Correct AnswerverifiedShow Answer

Which of the following is primarily responsible for the maternal effect?

Correct AnswerverifiedShow Answer

Most imprinted genes are silenced. What is one exception to this rule?

Correct AnswerverifiedShow Answer

In the gene that affects snail coiling, the ______ is responsible for the phenotype of the offspring.

Correct AnswerverifiedC

Which diseases are associated with imprinting?

Correct AnswerverifiedShow Answer

In the Igf2 gene, which allele is imprinted? Which is expressed?

Correct AnswerverifiedShow Answer

If the sperm cell contributes mitochondria to the oocyte, it is called _______.

Correct AnswerverifiedA

Heteroplasmy is associated with inheritance patterns involving

Correct AnswerverifiedShow Answer

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C

mtDNA stands for _ and cpDNA stands for _.

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C

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A

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