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Exam 16: Blood

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Question 41

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Erythropoietin (EPO)was first isolated from the urine of anemic patients who had high circulating levels of the hormone.Despite the presence of the hormone that stimulates red cell production,however,these patients were unable to produce adequate amounts of hemoglobin or red cells.Give some possible reasons that the patients' own EPO was unable to correct their anemia.

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Some other factor that is esse...

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Question 42

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The dissolution of fibrin by plasmin is known as ________.

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Question 43

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Name the two mechanisms and the factors involved that limit the extent of blood clotting within a vessel.

Platelets function in

A normal adult hematocrit would be approximately ________%.

The primary organ where erythropoietin is produced is the

________ are a group of diseases characterized by the abnormal growth and development of white blood cells,and ________ are diseases where patients have too few white blood cells.

Match the following terms with the correct descriptions. -Phagocytic,these cells make up the majority of WBCs.

The two main components of plasma are ________ and ________.Name two other components found in plasma.

Tissue factor is released in the

Explain how anticoagulant drugs can be useful to heart attack or stroke patients.

A study was done in 1998 by Dr.Benjamin Levine to explore the role of altitude training in athletic performance.First he trained athletes at low altitude,then measured their finish times in a 5 kilometer run.Then the athletes were placed into one of the following groups: I,living and training at high altitude; II,living at high altitude and training at low; or III,living and training at low altitude.The athletes were then retested in another low-altitude 5 K race.In this study,what are the control and experimental data? What are the dependent and independent variables? The results are expressed as average change in speed of each group.I: -3.4 sec.,II: +13.4 sec.,III: -26.7 sec.Graph and interpret the results.Did the results surprise you? Why or why not? Propose some explanations for the lower performance by the live high-train high group.Why wasn't there a live low-train high group?

Match the name of the pathological condition with its description. -genetic condition resulting in crescent moon-shaped red blood cells

The hormone that regulates the production of red blood cells is ________.

A hemoglobin molecule is composed of

The most abundant proteins in blood plasma are

Give two morphological characteristics of erythrocytes.Why is each advantageous to the cell?

Match each leukocyte to its normal percentage in a differential cell count. -monocytes

Sonja is 28 years old and weighs 132 lb (2.2 lb = 1 kg).Calculate the following values for her,assuming she is an average healthy adult. A.What is her approximate blood volume? B.What is her approximate plasma volume? C.Assuming a normal hematocrit,what is her volume of cellular elements? D.What is her typical RBC count? E.WBC? F.Differential count? G.Platelets? H.What hemoglobin level would you expect to find?

Mike has classical hemophilia,a clotting disorder,but his case is considered "mild." Contrary to popular belief,Mike doesn't usually have problematic bleeding episodes related to cutting himself; a more severe problem for him would be brought on by a sprained ankle or by having a full body impact,like falling off a horse and landing hard on the ground,injuries considered "closed." With what you have learned about blood coagulation,can you explain how this could be so? Assuming Mike is lacking factor VIII,which pathways does he depend on?