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For a mutation to become an allele it must occur in one of three possible locations.What are those three?

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in the sperm,egg,or ...

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What is a carcinogen?

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A mutagen that has b...

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What is the difference between mutagens and carcinogens?


A) All mutagens are carcinogens.
B) All carcinogens are mutagens.
C) Carcinogens are any substance that damages DNA and can lead to cancer.
D) B and C
E) None of the above; they are the same thing with different names

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A mutation is best described as an error in


A) DNA.
B) mRNA.
C) protein.
D) enzymes.
E) cell division.

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Is the way a protein folds important for its function?


A) Yes, protein function depends on the protein's 3-D structure.
B) Yes, because DNA mutations are caused by protein folding incorrectly.
C) No, as long as the sequence is correct.
D) No, as long as the protein is still soluble.
E) None of the above.

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How many alleles for a single trait are present in each human cell?


A) 1
B) 2
C) 23
D) 46
E) 4

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Permanent activation or overexpression of proto-oncogenes


A) turns tumor suppressors off.
B) is required for normal cell division.
C) has been linked to breast cancer.
D) keeps a cell from dividing.
E) turns tumor suppressors on.

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What would happen if a tumor suppressor,such as BRCA1,was mutated?


A) DNA may not be able to be repaired.
B) The cell cycle could continue without stopping when needed.
C) Cells would stop dividing and be unable to get through the cell cycle.
D) A and B only
E) All of the above.

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A newly identified mutation in mice,called "darkened dorsal," causes a dark stripe along the mouse's back.This mutation is located at a specific location on chromosome 2.A different sequence at this same chromosomal position results in a fur color pattern called "nonagouti." Based on this information,darkened dorsal and nonagouti are different


A) genes for fur color.
B) alleles for the same gene.
C) mutations of the same chromosome.
D) chromatids.
E) All of the above.

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Explain the effect of environmental mutagens in determining whether a woman with a mutation in one of her BRCA genes will actually get cancer.

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Even if a woman has a mutation in one of...

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In normal cells,tumor suppressors are


A) oncogenes.
B) not required.
C) carcinogens.
D) required for DNA repair or programmed cell death.
E) underexpressed.

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BRCA1 and BRCA2 are ___________,p53 is a ___________,and Her2 is a __________.


A) tumor-suppressor genes, tumor-suppressor gene, proto-oncogene
B) tumor-suppressor genes; proto-oncogene; tumor-suppressor gene
C) proto-oncogenes; tumor-suppressor gene; proto-oncogene
D) proto-oncogenes; tumor-suppressor gene; tumor-suppressor gene
E) proto-oncogenes; proto-oncogene; tumor-suppressor gene

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Mutations usually affect a protein's


A) size.
B) shape.
C) length.
D) electrical charge.
E) longevity.

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DNA mutations can


A) be detrimental.
B) be beneficial.
C) have no effect.
D) All of the above.
E) A or B only

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If one has an inherited allele known to be linked to an increased risk of cancer,what are some suggestions to lower the risk?

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Answers will vary,but generally,avoid ex...

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In a cell with the following mutations,which would you expect to be MOST likely to cause tumors?


A) BRCA1 and BRCA2
B) BRCA1 and p53 mutation
C) BRCA1, BRCA2, Her2, and p53 mutations
D) BRCA1, BRCA2, and p53 mutations
E) BRCA1, Her2, and p53 mutations

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If you avoid dangerous chemicals and radiation for your entire life,you prevent all mutations in your DNA.

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Inherited mutations


A) predispose individuals to cancer.
B) come from DNA sequence mistakes contained in germ cells.
C) can come from one's mother or father.
D) are errors in DNA that go uncorrected.
E) All of the above.

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Which sequence is the complementary DNA sequence of ATG GGC CTG?


A) ATG GGC CTG
B) TAC CCG GAG
C) TUC CCG GUC
D) TAC CCG GAC
E) TAC CCC GAC

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"A person who inherits a mutation in a cell cycle regulatory gene will develop cancer." Is this a true statement? Explain.

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It takes more than one mutatio...

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