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The nurse is preparing to give trimethoprim-sulfamethoxazole (TMP-SMX) to a patient and notes a petechial rash on the patient's extremities.The nurse will perform which action?


A) Hold the dose and notify the provider.
B) Request an order for a blood glucose level.
C) Request an order for a BUN and creatinine level.
D) Request an order for diphenhydramine (Benadryl) .

Correct Answer

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Which actions can contribute to bacterial resistance to antibiotics?


A) Frequent use of antibiotics
B) Giving large doses of antibiotics
C) Skipping doses
D) Taking a full course of antibiotics
E) Treating viral infections with antibiotics

Correct Answer

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The nurse is preparing to administer amoxicillin (Amoxil) to a patient and learns that the patient previously experienced a rash when taking penicillin.Which action will the nurse take?


A) Administer the amoxicillin and have epinephrine available.
B) Ask the provider to order an antihistamine.
C) Contact the provider to discuss using a different antibiotic.
D) Request an order for a beta-lactamase resistant drug.

Correct Answer

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C

A female patient who is taking trimethoprim-sulfamethoxazole (TMP-SMZ) (Bactrim,Septra) to treat a urinary tract infection reports vaginal itching and discharge.The nurse will perform which action?


A) Ask the patient if she might be pregnant.
B) Reassure the patient that this is a normal side effect.
C) Report a possible superinfection to the provider.
D) Suspect that the patient is having a hematologic reaction.

Correct Answer

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A female patient who is allergic to penicillin will begin taking an antibiotic to treat a lower respiratory tract infection.The patient tells the nurse that she almost always develops a vaginal yeast infection when she takes antibiotics and that she will take fluconazole (Diflucan) with the antibiotic being prescribed.Which macrolide order would the nurse question for this patient?


A) Azithromycin (Zithromax)
B) Clarithromycin (Biaxin)
C) Erythromycin (E-Mycin)
D) Fidaxomicin (Dificid)

Correct Answer

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The nurse is reviewing a patient's chart prior to administering gentamicin (Garamycin) and notes that the last serum peak drug level was 9 mcg/mL and the last trough level was 2 mcg/mL.What action will the nurse take?


A) Administer the next dose as ordered.
B) Obtain repeat peak and trough levels before giving the next dose.
C) Report possible drug toxicity to the patient's provider.
D) Report a decreased drug therapeutic level to the patient's provider.

Correct Answer

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The patient will begin taking penicillin G procaine (Wycillin) .The nurse notes that the solution is milky in color.What action will the nurse take?


A) Call the pharmacist and report the milky color.
B) Add normal saline to dilute the medication.
C) Call the physician and report the milky appearance.
D) Administer the medication as ordered by the physician.

Correct Answer

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The nurse is preparing to administer trimethoprim-sulfamethoxazole (TMP-SMX) to a patient who is being treated for a urinary tract infection.The nurse learns that the patient has type 2 diabetes mellitus and takes a sulfonylurea oral antidiabetic drug.The nurse will monitor this patient closely for which effect?


A) Headaches
B) Hypertension
C) Hypoglycemia
D) Superinfection

Correct Answer

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A patient taking trimethoprim-sulfamethoxazole (TMP-SMX) to treat a urinary tract infection complains of a sore throat.The nurse will contact the provider to request an order for which laboratory test(s) ?


A) Complete blood count with differential
B) Throat culture
C) Urinalysis
D) Coagulation studies

Correct Answer

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The nurse is caring for a 7-year-old patient who will receive oral antibiotics.Which antibiotic order will the nurse question for this patient?


A) Azithromycin (Zithromax)
B) Clarithromycin (Biaxin)
C) Clindamycin (Cleocin)
D) Tetracycline (Sumycin)

Correct Answer

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The nurse is preparing to begin a medication regimen for a patient who will receive intravenous ampicillin and gentamicin.Which is an important nursing action?


A) Administer each antibiotic to infuse over 15 to 20 minutes.
B) Order serum peak and trough levels of ampicillin.
C) Prepare the schedule so that the drugs are given at the same time.
D) Set up separate tubing sets for each drug labeled with the drug name and date.

Correct Answer

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The nurse is preparing to administer the first dose of intravenous ceftriaxone (Rocephin) to a patient.When reviewing the patient's chart,the nurse notes that the patient previously experienced a rash when taking amoxicillin.What is the nurse's next action?


A) Administer the drug and observe closely for hypersensitivity reactions.
B) Ask the provider whether a cephalosporin from a different generation may be used.
C) Contact the provider to report drug hypersensitivity.
D) Notify the provider and suggest an oral cephalosporin.

Correct Answer

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The nurse is preparing to administer an antibiotic to a patient who has been receiving the antibiotic for 2 days after a culture was obtained.The nurse notes increased erythema and swelling,and the patient has a persistent high fever of 39° C.What is the nurse's next action?


A) Administer the antibiotic as ordered.
B) Contact the provider to request another culture.
C) Discuss the need to add a second antibiotic with the provider.
D) Review the sensitivity results from the patient's culture.

Correct Answer

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The nurse is preparing to give a dose of oral clindamycin (Cleocin) to a patient who is being treated for a skin infection caused by Staphylococcus aureus.The patient has had several doses of the medication and reports having nausea.Which action will the nurse take next?


A) Administer the next dose when the patient has an empty stomach.
B) Hold the next dose and contact the patient's provider.
C) Instruct the patient to take the next dose with a full glass of water.
D) Request an order for an antacid to give along with the next dose.

Correct Answer

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The nurse is caring for a patient who is taking trimethoprim-sulfamethoxazole (TMP-SMX) .The nurse learns that the patient takes an angiotensin-converting enzyme (ACE) inhibitor.To monitor for drug interactions,the nurse will request an order for which laboratory test(s) ?


A) A complete blood count
B) BUN and creatinine
C) Electrolytes
D) Glucose

Correct Answer

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The nurse is teaching a nursing student about the minimal effective concentration (MEC) of antibiotics.Which statement by the nursing student indicates understanding of this concept?


A) "A serum drug level greater than the MEC ensures that the drug is bacteriostatic."
B) "A serum drug level greater than the MEC broadens the spectrum of the drug."
C) "A serum drug level greater than the MEC helps eradicate bacterial infections."
D) "A serum drug level greater than the MEC increases the therapeutic index."

Correct Answer

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The nurse is caring for a patient who is receiving an intravenous antibiotic.The patient has a serum drug trough of 1.5 mcg/mL.The normal trough for this drug is 1.7 to 2.2 mcg/mL.What will the nurse expect the patient to experience?


A) Inadequate drug effects
B) Increased risk for superinfection
C) Minimal adverse effects
D) Slowed onset of action

Correct Answer

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The nurse is caring for several patients who are receiving antibiotics.Which order will the nurse question?


A) Azithromycin (Zithromax) 500 mg IV in 500 mL fluid
B) Azithromycin (Zithromax) 500 mg PO once daily
C) Erythromycin 300 mg IM QID
D) Erythromycin 300 mg PO QID

Correct Answer

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The nurse is caring for a 70-kg patient who is receiving gentamicin (Garamycin) 85 mg 4 times daily.The patient reports experiencing ringing in the ears.The nurse will contact the provider to discuss


A) decreasing the dose to 50 mg QID.
B) giving the dose 3 times daily.
C) obtaining a serum drug level.
D) ordering a hearing test.

Correct Answer

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C

The nurse is preparing to administer intravenous gentamicin to an infant through an intermittent needle.The nurse notes that the infant has not had a wet diaper for several hours.The nurse will perform which action?


A) Administer the medication and give the infant extra oral fluids.
B) Contact the provider to request adding intravenous fluids when giving the medication.
C) Give the medication and obtain a serum peak drug level 45 minutes after the dose.
D) Hold the dose and contact the provider to request a serum trough drug level.

Correct Answer

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D

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