Question 1

The multidrug resistant pumps in many bacterial cell membranes function by

Accepted Answer

A)  bacterial chromosomal mutations.
B)  synthesis of enzymes that alter drug structure.
C)  removing the drug from the cell when it enters.

Question 2

A ratio of the dose of the drug that is toxic to humans versus the minimum effective dose for that pathogen is assessed to predict the potential for toxic drug reactions.This is called the

Accepted Answer

A)  Kirby-Bauer technique.
B)  antibiogram.
C)  E-test.
D)  minimum inhibitory concentration (MI
C)  .
E)  therapeutic index (TI) .

Question 3

A clinical microbiologist makes serial dilutions of several antimicrobials in broth,and then incubates each drug dilution series with a standard amount of a patient's isolated pathogen.What is this microbiologist setting up?

Accepted Answer

A)  Kirby-Bauer technique
B)  antibiogram
C)  E-test
D)  minimum inhibitory concentration (MI
C)  test
E)  therapeutic index (TI)

Question 4

Microbial resistance resulting from mutation occurs because

Accepted Answer

A)  prokaryotic genomes undergo mutation rapidly.
B)  prokaryotic genomes undergo mutation often.
C)  short generation times accumulate mutations in populations.
D)  mutations are passed between organisms.
E)  All of the choices are correct.

Question 5

Broad-spectrum drugs that disrupt the body's normal biota often cause

Accepted Answer

A)  nephrotoxicity.
B)  superinfections.
C)  allergic reactions.
D)  drug toxicity.

Question 6

Which of the following blocks HIV binding to host cell receptors?

Accepted Answer

A)  AZT
B)  acyclovir
C)  nevirapine
D)  Fuzeon
E)  amantidine

Question 7

Acyclovir is used to treat infections caused by:

Accepted Answer

A)  influenza A virus.
B)  HIV.
C)  herpes simplex virus.
D)  respiratory syncytial virus.
E)  hepatitis C virus.

Question 8

Antimicrobials effective against a wide variety of microbial types are termed

Accepted Answer

A)  antibiotics.
B)  narrow-spectrum drugs.
C)  semisynthetic drugs.
D)  synthetic drugs.
E)  broad-spectrum drugs.

Question 9

Which of the following is not used to treat malaria?

Accepted Answer

A)  quinine
B)  chloroquine
C)  metronidazole
D)  primaquine
E)  meflaquine

Question 10

What type of chemical will allow some bacteria to be resistant to many penicillins?

Accepted Answer

A)  synercid
B)  penicillinase
C)  aztreonam
D)  clavulanic acid
E)  imipenem

Question 11

Newer,more expensive antimicrobials are always better to use than cheaper,older drugs.

Accepted Answer

A) True 
 B)False

Question 12

An antibiotic of the penicillin family is penicillin
G.

Accepted Answer

A) True 
 B)False

Question 13

Over 50 percent of all sales of medically important antibiotics in the United States are for livestock use.Why is this problematic for humans?

Accepted Answer

A)  The livestock will become resistant to the antibiotics and not respond to treatment when they have infections.
B)  Resistant bacteria grow in the animals and may then be passed to humans.
C)  The use of antibiotics for livestock means that there are not enough for use in the human population.
D)  The animals may become sick from the antibiotic ingestion.

Question 14

A drug exhibiting which therapeutic index value would be the safest,most effective to use on a patient?

Accepted Answer

A)  20
B)  10
C)  1
D)  0.1
E)  Any choice would be equally effective.

Exam 12: Drugs, Microbes, host-The Elements of Chemotherapy

Microbial resistance resulting from mutation occurs because

Correct Answer
verified

Over 50 percent of all sales of medically important antibiotics in the United States are for livestock use.Why is this problematic for humans?

Correct Answer
verified

Which of the following is not used to treat malaria?

Correct Answer
verified

A clinical microbiologist makes serial dilutions of several antimicrobials in broth,and then incubates each drug dilution series with a standard amount of a patient's isolated pathogen.What is this microbiologist setting up?

Correct Answer
verified

Acyclovir is used to treat infections caused by:

Correct Answer
verified

A ratio of the dose of the drug that is toxic to humans versus the minimum effective dose for that pathogen is assessed to predict the potential for toxic drug reactions.This is called the

Correct Answer
verified

Newer,more expensive antimicrobials are always better to use than cheaper,older drugs.

Correct Answer
verified

The multidrug resistant pumps in many bacterial cell membranes function by

Correct Answer
verified

Which of the following blocks HIV binding to host cell receptors?

Correct Answer
verified

An antibiotic of the penicillin family is penicillin G.

Correct Answer
verified

Broad-spectrum drugs that disrupt the body's normal biota often cause

Correct Answer
verified

Antimicrobials effective against a wide variety of microbial types are termed

Correct Answer
verified

A drug exhibiting which therapeutic index value would be the safest,most effective to use on a patient?

Correct Answer
verified

What type of chemical will allow some bacteria to be resistant to many penicillins?

Correct Answer
verified

Exam 12: Drugs, Microbes, host-The Elements of Chemotherapy

Microbial resistance resulting from mutation occurs because

Correct AnswerverifiedShow Answer

Over 50 percent of all sales of medically important antibiotics in the United States are for livestock use.Why is this problematic for humans?

Correct AnswerverifiedShow Answer

Which of the following is not used to treat malaria?

Correct AnswerverifiedShow Answer

A clinical microbiologist makes serial dilutions of several antimicrobials in broth,and then incubates each drug dilution series with a standard amount of a patient's isolated pathogen.What is this microbiologist setting up?

Correct AnswerverifiedShow Answer

Acyclovir is used to treat infections caused by:

Correct AnswerverifiedShow Answer

A ratio of the dose of the drug that is toxic to humans versus the minimum effective dose for that pathogen is assessed to predict the potential for toxic drug reactions.This is called the

Correct AnswerverifiedShow Answer

Newer,more expensive antimicrobials are always better to use than cheaper,older drugs.

Correct AnswerverifiedShow Answer

The multidrug resistant pumps in many bacterial cell membranes function by

Correct AnswerverifiedShow Answer

Which of the following blocks HIV binding to host cell receptors?

Correct AnswerverifiedShow Answer

An antibiotic of the penicillin family is penicillin G.

Correct AnswerverifiedShow Answer

Broad-spectrum drugs that disrupt the body's normal biota often cause

Correct AnswerverifiedShow Answer

Antimicrobials effective against a wide variety of microbial types are termed

Correct AnswerverifiedShow Answer

A drug exhibiting which therapeutic index value would be the safest,most effective to use on a patient?

Correct AnswerverifiedShow Answer

What type of chemical will allow some bacteria to be resistant to many penicillins?

Correct AnswerverifiedShow Answer

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