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Anti-human-gamma-globulin antiserum is often used in


A) direct fluorescent antibody tests.
B) complement fixation test.
C) radioimmunoassay.
D) indirect fluorescent antibody tests.

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Blood for transfusion is frequently tested for AIDS by using the


A) complement fixation test.
B) radioimmunoassay test.
C) ELISA method.
D) RIA test.

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Serological tests are most often conducted in


A) test tubes.
B) flasks.
C) microtiter plates.
D) graduated cylinders.

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DNA vaccines are dangerous due to the possibility of the DNA causing reversion in the inactivated pathogen.

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Almost all of the antibodies found in a newborn are


A) the result of infection.
B) self-made.
C) IgM.
D) the result of passive immunity.

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Substances that are contained in vaccines to help induce a better immune response are called


A) primary substances.
B) secondary substances.
C) adjuvants.
D) adjuncts.

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A poorly understood, yet promising type of vaccine that causes the host to produce microbial antigens for a short time involves the use of


A) subunits.
B) DNA.
C) alum.
D) toxoids.
E) glycoproteins.

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The risk of serious illness from measles is 500 times greater than from vaccination against the disease.

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The scientist who made variolation safer and more effective was


A) Pasteur.
B) Jenner.
C) Metchnikoff.
D) Fleming.

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Inactivated immunizing agents are prepared by treatment with


A) alcohol.
B) phenol.
C) formalin.
D) histamine.

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An immune complex is defined as


A) antigen combined with antigen.
B) antigen combined with antibody.
C) antibody combined with antibody.
D) complement combined with LPS.

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Precipitation reactions carried out in agarose are called


A) hemagglutination tests.
B) complement fixation tests.
C) immunodiffusion tests.
D) RIA tests.

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Peptide vaccines have proven to be cheap and very immunogenic.

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Which antibodies cross the placenta and protect the fetus?


A) IgA
B) IgG
C) IgM
D) IgD

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Since many childhood diseases such as mumps and measles are rare now within the US, why is it still important for children to be immunized against them?


A) If we lose herd immunity by removing mandatory vaccination, our population will become susceptible to these illnesses again in a short period of time.
B) There is always the likelihood that an individual from another country could import one of these illnesses into the US, sparking an outbreak of new infections, if we aren't all properly vaccinated.
C) By keeping the population vaccinated, we keep incidence rates of these illnesses very low. This helps to protect people that cannot be vaccinated (very young children, pregnant women, immunocompromised individuals, the elderly) .
D) Many of these diseases are HIGHLY contagious, and commonly through respiratory droplet (airborne) transmission. This makes an outbreak within a susceptible population very possible. Keeping the population resistant through mandatory vaccination prevents this possibility.
E) All of the options are correct.

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Attenuated agents


A) may induce immunity after a single dose.
B) may cause disease in immunocompromised individuals.
C) multiply in the body.
D) may revert or mutate to disease-causing strains.
E) All of the choices are correct.

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The Salk vaccine


A) protects against nervous system and gastrointestinal infection.
B) protects only against gastrointestinal infection.
C) is a subunit vaccine.
D) protects only against nervous system infection.
E) protects against nervous system and gastrointestinal infection AND is a subunit vaccine.

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Alum is an adjuvant.

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The most common adjuvant is


A) ethanol.
B) formalin.
C) alum.
D) aluminum.
E) alum AND aluminum.

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Anti-human-gamma-globulin antiserum is often used in


A) direct fluorescent antibody tests.
B) indirect ELISA.
C) Western blot.
D) indirect fluorescent antibody tests.
E) indirect ELISA, Western blot AND indirect fluorescent antibody tests.

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