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Recombinant DNA technology is useful in producing:


A) artificial hearts and kidneys.
B) insulin and growth hormone.
C) new organs for transplant.
D) livestock.
E) clones.

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Which is NOT a component of a nucleotide?


A) sugar
B) nitrogenous base
C) phosphorous containing group
D) double helix
E) all of the above

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How should blood-containing clothes from a victim be packaged?


A) in breathable paper after blood has dried
B) in an airtight clear plastic container
C) in an airtight metal container
D) in breathable paper while blood is still wet
E) in a metal paint can

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The molecular structure of DNA was deduced by:


A) Linus Pauling.
B) Francis Crick.
C) James Watson.
D) Gregor Mendel.
E) both B and C

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STRs normally consist of repeating sequences of:


A) 3-7 bases.
B) 18-2 bases.
C) 13-17 bases.
D) 8-12 bases.
E) 1-2 bases.

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Which statement about tandem repeats is NOT true?


A) It is thought that they may act as spacers between the coded regions of DNA.
B) Their origin is a mystery.
C) They are of no forensic interest.
D) More than 30% of the human genome is composed of these repeating units.
E) More than one STR can be analyzed at once in a process called multiplexing.

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In which hereditary disease does abnormal hemoglobin differ from normal hemoglobin by only a single amino acid?


A) phenylketonuria
B) cystic fibrosis
C) sickle-cell anemia
D) hemophilia
E) albinism

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List and briefly describe the process of PCR.

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Polymerase Chain Reaction (PCR) is a wid...

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During gel electrophoresis the DNA is:


A) extracted from the cell nuclei.
B) visualized using x-rays.
C) cut into fragments.
D) undergoing hybridization.
E) separated by fragment size.

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Information from the Human Genome Project will:


A) help to reveal the role and implications of evolution.
B) reveal the location of a gene on a particular chromosome.
C) be useful for diagnosing and treating genetic diseases.
D) aid in understanding the underlying causes of cancer.
E) all of the above

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Means to detect the amelogenin gene are included in commercial STR kits used in crime labs because the gene allows determination of:


A) gender.
B) age.
C) blood type.
D) eye color.
E) ethnicity.

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What is the number of nitrogenous bases needed to code for a specific amino acid?


A) 4
B) 5
C) 6
D) 3
E) 2

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Which component of DNA forms the backbone of the molecule?


A) phosphate group
B) nitrogenous base
C) sugar
D) adenine
E) both A and C

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Which statement about RFLPs is NOT true?


A) There is little variation in the number of repeats from person to person.
B) All humans have the same type of repeats.
C) Analysis is undertaken using a technique called Southern blotting.
D) Restriction enzymes are used to cut RFLPs from the DNA helix.
E) Typically a core repeat sequence would consist of 15-30 bases.

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The specific proteins produced by a cell are directly related to the:


A) number of mitochondria in the cell.
B) length of the chromosomes.
C) sequence of sugars and phosphates in the cell.
D) sequence of nucleotides in the DNA of the cell.
E) size of the cell.

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CODIS is a national system of:


A) shared databases of DNA typing information from convicted felons and crime scene evidence.
B) vastly enhanced 911 emergency systems.
C) computers to track the movement of sex offenders released from prison.
D) standards for forensic science evaluators.
E) crime laboratory directors.

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___________ region(s) of mitochondrial DNA have been found to be highly variable in the human population for forensic determinations.


A) three
B) two
C) four
D) one
E) five

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