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With a few exceptions, each human cell contains DNA in its nucleus.Which statement about any cell containing DNA is true?


A) The entire genome is expressed in each cell.
B) The cell discards some of its DNA so that only genes with a function in that cell are retained.
C) Cells synthesize RNA transcripts from its DNA before discarding the DNA.
D) Different genes may be expressed at different times in a single cell.
E) Cell functioning differs depending on the DNA present in the cell.

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According to the chemical evolution theory of the origin of life, which statement is true?


A) Oxygen (O2) was necessary for formation of the simple molecules of life.
B) Earth's early environments, with energy provided by the sun, may have been capable of producing complex life forms.
C) Small molecules that serve as the building blocks of living organisms can form under conditions that might have existed on Earth in its early history.
D) The chemical content of meteorites indicates that simple molecules of life could not have been synthesized in extraterrestrial environments.
E) The simple molecules of life can form only in a simulated atmosphere that is sparked with electricity.

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Miller and Urey set up an experimental "atmosphere" composed of gases thought to be present in Earth's early atmosphere.They simulated lightning with the application of electricity and looked for the monomers used to build living organisms.Subsequent experiments using additional gases that probably were present in the early Earth environment resulted in a more diverse list of organic products.Which compounds were absent from the products of Miller and Urey's experiments?


A) Nitrogenous bases found in DNA
B) Simple proteins
C) 20 amino acids
D) Six-carbon sugars
E) Uracil, a nitrogenous base

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Which statement about the "RNA world" model is true?


A) Self-catalytic DNA was the first nucleic acid.
B) DNA was translated directly into protein.
C) Ribozymes are able to catalyze the formation of peptide linkages.
D) RNA was reverse transcribed into DNA before being transcribed and translated into proteins.
E) All RNA sequences act as ribozymes.

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Which statement about the addition of a nucleotide onto a growing nucleic acid is true?


A) A hydrolysis reaction occurs between the last nucleotide in the chain and the new nucleotide.
B) The phosphate on the added nucleotide attaches to the 5′ carbon atom of a sugar on the chain.
C) The resulting bond between nucleotides is called a glycosidic linkage.
D) Because of how each nucleotide is added to the chain, nucleic acids are said to grow in the 5′-to-3′ direction.
E) A bond forms between the phosphate of the last nucleotide and the pentose sugar of the new nucleotide.

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Complementary base pairing between nucleotides makes which process possible?


A) Hydrolysis of DNA
B) Formation of phosphodiester bonds in polynucleotides
C) DNA replication prior to cell division
D) Movement of mRNA from nucleus to cytoplasm
E) Biosynthesis of nucleotide building blocks by a cell

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Refer to the figure below illustrating Louis Pasteur's experiment on spontaneous generation. Refer to the figure below illustrating Louis Pasteur's experiment on spontaneous generation.   Why was the neck broken on one flask but not the other? A)  To ensure that conditions were the same in both experimental setups B)  To prevent contaminants from getting in through the neck C)  To allow dust to enter into the broken flask but not the unbroken one D)  To show that the neck of the flask does not introduce an added variable to the experiment E)  To allow air to enter the control flask Why was the neck broken on one flask but not the other?


A) To ensure that conditions were the same in both experimental setups
B) To prevent contaminants from getting in through the neck
C) To allow dust to enter into the broken flask but not the unbroken one
D) To show that the neck of the flask does not introduce an added variable to the experiment
E) To allow air to enter the control flask

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Miller and Urey's 1954 hot chemistry experiment was based on the assumption that Earth's early atmosphere contained water (H2O) vapor, methane, hydrogen, and ammonia.Subsequent research showed that volcanoes released carbon dioxide (CO2) , hydrogen sulfide (H2S) , and sulfur dioxide (SO2) around 4 billion years ago.In response to this evidence, scientists concluded that


A) no synthesis of prebiotic molecules was possible on early Earth.
B) the experiment needed to be repeated with the inclusion of CO2, SO2, and H2O.
C) the experiment needed to be repeated with the inclusion of CO2, SO2, and H2S.
D) the experiment needed to be repeated with the inclusion of CO2, SO2, and H2S, and the exclusion of the original gases.
E) the experiment needed to be repeated in the vicinity of an active volcano and with the inclusion of CO2, SO2, and H2S.

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Which factor contributes to the strength of the intermolecular interaction between two DNA strands in a double helix?


A) Hydrogen bonds between purines and pyrimidines
B) Phosphodiester bonds between the nitrogenous bases
C) Strong hydrogen bonds between the sugar and phosphate groups
D) Its double-helix shape
E) The direct bonding of the base to the phosphate molecule

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All of the following bases are found in DNA except


A) thymine.
B) adenine.
C) uracil.
D) guanine.
E) cytosine.

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Scientists hypothesize that nonliving protocells developed as a precursor to living cells.Which statement can best be used as evidence to support this hypothesis?


A) Both l- and d-isomers of amino acids were shown to be able to diffuse through the membranes of protocells synthesized in a lab.
B) The same fatty acids found in the membranes of living organisms are capable of being used to synthesize protocells that have an internal space filled with water.
C) Simple fatty acids shown to be synthesized in primitive Earth simulation experiments are able to self-assemble into protocell structures when placed in water.
D) Lab experiments showed that nucleic acids in the interior of the protocells replicated themselves using nucleotides supplied in the medium surrounding the protocells.
E) Some metabolic reactions that take place in modern cells can also take place in the interiors of protocells synthesized in a lab.

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What evidence lent strong support to J.William Schopf's hypothesis that the 3.5-billion-year-old fossil he discovered in Australia was that of ancient cells?

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Schopf examined both chemical and struct...

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Which is evidence that supports the hypothesis that DNA could have evolved from RNA?


A) The discovery that retroviruses have an enzyme that catalyzes DNA synthesis from RNA
B) Evidence of the early emergence on Earth of chemical reactions that resulted in monomers
C) Evidence of the nearly spontaneous formation of lipid micelles on Earth
D) Evidence of the prebiotic chemical generation of cell-like compartments
E) The chemical traces of life found on meteorites

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Laboratory experiments with pure samples of either the d- or l-isomer of the amino acid aspartic acid show that these samples slowly change to an equilibrium mixture of both optical isomers.The rate of change is extremely slow, requiring a few million years to billions of years to complete, depending on temperature and availability of water.If scientists wanted to locate amino acids as evidence of past life on the planet Mars, what region would be best to study, given that any life on Mars may have gone extinct early in its history?


A) Any region
B) Areas likely covered with liquid water in the past
C) Areas of volcanic activity
D) Polar ice regions
E) Impact craters

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The diversity found among DNA molecules is due to the sequence of _______.

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Refer to the figure below showing two strands of DNA. Refer to the figure below showing two strands of DNA.   How many hydrogen bonds would there be in a DNA sequence of ten base pairs in which there are five A-T and five C-G pairs? A)  5 B)  10 C)  15 D)  25 E)  18 How many hydrogen bonds would there be in a DNA sequence of ten base pairs in which there are five A-T and five C-G pairs?


A) 5
B) 10
C) 15
D) 25
E) 18

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Refer to the figure below showing the Miller‒Urey experiment. Refer to the figure below showing the Miller‒Urey experiment.   Research conducted later than the Miller‒Urey experiment showed that volcanic activity 4 billion years ago injected other gases, such as SO<sub>2</sub>, into Earth's early environment.This information led to the conclusion that A)  the original Miller-Urey experiment did not produce meaningful data. B)  a modified experiment should be performed in which other gases would be added to the initial heated solution. C)  the experiment required a longer running time to see whether the other gases would be produced. D)  the beaker of condensed liquid and compounds should be heated in the presence of the additional gases. E)  the Miller‒Urey experiment did not require modification, since cellular life existed earlier than 4 billion years ago. Research conducted later than the Miller‒Urey experiment showed that volcanic activity 4 billion years ago injected other gases, such as SO2, into Earth's early environment.This information led to the conclusion that


A) the original Miller-Urey experiment did not produce meaningful data.
B) a modified experiment should be performed in which other gases would be added to the initial heated solution.
C) the experiment required a longer running time to see whether the other gases would be produced.
D) the beaker of condensed liquid and compounds should be heated in the presence of the additional gases.
E) the Miller‒Urey experiment did not require modification, since cellular life existed earlier than 4 billion years ago.

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Some trace metals such as molybdenum and rhenium are soluble in oxygenated water.These rare metals first appeared in sedimentary rocks on Earth 2.5 billion years ago, where previously they occurred as chemical compounds in minerals.The appearance of these metals at this time indicates that


A) cyanobacteria used all available oxygen until 2.5 billion years ago.
B) meteorites from Mars carried oxygen to Earth.
C) comets brought oxygen to Earth.
D) there was no life on Earth until 2.5 billion years ago.
E) there was no atmospheric oxygen on Earth until 2.5 billion years ago.

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Chemical reaction rates vary depending on the concentrations of reactants.In which primitive Earth environment would conditions have shifted reactant concentrations to favor increased polymerization of monomers?


A) Rocky outcroppings with full sun exposure
B) Deep, wide freshwater lakes
C) Hot, sandy beaches
D) Shallow ponds with clay bottoms
E) Thermal vents deep in a salty ocean

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Redi performed experiments using raw meat and _______ to disprove the idea of spontaneous generation.

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