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Which of the following supports the contention that schizophrenia is associated with brain damage?


A) Control subjects are more likely to show neurological symptoms.
B) The size of the lateral ventricles increases in schizophrenic patients.
C) The neurological symptoms noted in schizophrenia are unique to this disorder.
D) The size of the lateral ventricles decreases in schizophrenic patients.
E) Older people, who have already lost substantial numbers of neurons, are more likely to develop schizophrenia than are younger people.

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Adoption and twin studies suggest that schizophrenia is a ________ trait.

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The incidence of schizophrenia may vary as a function of season because


A) birthing during the winter represents a stressor that impairs dopamine function.
B) a fetus born during the late summer is more likely to have experienced a viral infection during the second trimester.
C) immune function is generally enhanced during the winter months.
D) a fetus born in late winter may be exposed to a viral infection during the second trimester.
E) people are more likely to be outdoors during the early fall leading to greater risk of viral infection.

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A drug that binds with high affinity to a receptor, but has less efficacy than the endogenous transmitter, would be termed a(n)


A) pseudo-agonist
B) antagonist.
C) partial agonist.
D) autoreceptor agonist.
E) autoreceptor antagonist.

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Describe the interaction between sleep and depression.

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Depression is accompanied by disorder of...

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A drug such as aripiprazole counters the positive, negative, and cognitive symptoms of schizophrenia because this drug


A) is a pseudo-agonist at dopamine receptors in the VTA.
B) is an antagonist at dopamine receptors in the prefrontal cortex and nucleus accumbens.
C) causes the release of dopamine in brain.
D) is a partial agonist at dopamine receptors in the prefrontal cortex and nucleus accumbens.
E) blocks the release of dopamine in brain.

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An important function of monoamine oxidase is to


A) provide the precursor for the catecholamines.
B) convert dopamine into norepinephrine.
C) convert norepinephrine into epinephrine.
D) convert catecholamines and serotonin into inactive forms.
E) speed up the digestion of cheese within the gut.

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The symptoms of schizophrenia are more likely in a person whose


A) mother experienced obstetric complications.
B) father was under the age of 20.
C) birth occurred during the summer months.
D) mother had adequate nutrition during the pregnancy.
E) mother was obese.

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Which of the following is true of the seasonality effect?


A) Schizophrenia is more likely to occur for a person born in September and October.
B) The seasonality effect rarely occurs in rural settings.
C) The seasonality effect is mostly due to indoor smoking by the mother during the winter.
D) The seasonality effect is enhanced when fall temperatures are higher than normal.
E) Families living in crowded cities do not show the seasonality effect.

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A major problem for the use of lithium in psychiatry is that


A) lithium dulls thought processes.
B) there is a narrow therapeutic index for lithium.
C) lithium may not work in up to 50 percent of patients.
D) lithium is an expensive treatment.
E) lithium reduces appetite and body weight.

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An important function of ________ is to convert catecholamines and serotonin into inactive forms.

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Describe the types of evidence that support the proposition that alteration of prenatal development can contribute to the causation of schizophrenia.

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Epidemiological studies show that season...

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Analysis of the childhood behavior of schizophrenics have found that these children show ________ than do their normal siblings or normal peers.


A) more overall activity
B) fewer abnormal movements
C) more negative affect in their facial expressions
D) less overall activity
E) more symmetrical facial features

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The likelihood of developing schizophrenia increases to 31 percent for a person with ________ and ________.


A) birth complications; stress during adulthood
B) a mother who consumed a high-fat diet dieting pregnancy; a family history of schizophrenia
C) an identical twin who is normal; physical anomalies
D) a family history of schizophrenia; physical anomalies
E) minor physical anomalies; who was born during the summer months

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Which of the following is true of brain development and schizophrenia?


A) Rapid neuron loss occurs in early childhood in schizophrenia with little subsequent loss during adulthood.
B) Schizophrenics show rapid neuron loss that occurs in early adulthood, but not continuous neuron loss.
C) Schizophrenia shows the same degenerative pattern as is noted in Alzheimer's disease.
D) Schizophrenia shows the same degenerative pattern as is noted in Parkinson's disease.
E) Schizophrenia involves the creation of new, but abnormal, neurons.

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Studies suggest that schizophrenia may be associated with an increased number of ________ receptors within the brain.

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An alternative to lithium for the treatment of bipolar disorder is the use of


A) anticonvulsant drugs.
B) MAO inhibitors.
C) cocaine or amphetamine.
D) chlordiazepoxide.
E) ketamine

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The ________ sensory system is most likely to be involved in a schizophrenic hallucination.


A) visual
B) tactile
C) kinesthetic
D) auditory
E) olfactory

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Describe the types of evidence that support the proposition that alteration of prenatal development can contribute to the causation of schizophrenia.

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Epidemiological studies show that season...

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The capacity of an antischizophrenic drug to produce tardive dyskinesia may result from


A) subsensitivity of dopamine receptors.
B) reduced release of dopamine.
C) enhanced release of dopamine.
D) supersensitivity of dopamine receptors.
E) degeneration of dopamine neurons in the substantia nigra.

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