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Use the figure and the following description to answer the question(s) below. -Which of the boxes marked 1-4 correspond to plants with a heterozygous genotype?


A) 1
B) 1 and 2
C) 1, 2, and 3
D) 2 and 3
E) 2, 3, and 4

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Which of the following statements about independent assortment and segregation is correct?


A) The law of independent assortment requires describing two or more genes relative to one another.
B) The law of segregation requires describing two or more genes relative to one another.
C) The law of segregation requires having two or more generations to describe.
D) The law of independent assortment is accounted for by observations of prophase I.
E) The law of segregation is accounted for by anaphase of mitosis.

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Albinism is an autosomal (not sex-linked) recessive trait. A man and woman are both of normal pigmentation, but both have one parent who is albino (without melanin pigmentation) . What is the probability that their first female child will have albinism?


A) 0
B) 1/8
C) 1/2
D) 1/4
E) 1/3

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Radish flowers may be red, purple, or white. A cross between a red-flowered plant and a white-flowered plant yields all-purple offspring. The flower color trait in radishes is an example of which of the following?


A) a multiple allelic system
B) sex linkage
C) codominance
D) incomplete dominance

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Use the figure and the following description to answer the question(s) below. -Which of the boxes marked 1-4 correspond to plants with dark leaves?


A) 1 only
B) 1 and 2
C) 2 and 3
D) 4 only
E) 1, 2, and 3

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The following question(s) refer to the pedigree chart in the accompanying figure for a family, some of whose members exhibit the dominant trait, W. Affected individuals are indicated by a dark square or circle. The following question(s)  refer to the pedigree chart in the accompanying figure for a family, some of whose members exhibit the dominant trait, W. Affected individuals are indicated by a dark square or circle.   -What is the probability that individual III-1 is Ww? A)  3/4 B)  1/4 C)  2/4 D)  2/3 E)  1 -What is the probability that individual III-1 is Ww?


A) 3/4
B) 1/4
C) 2/4
D) 2/3
E) 1

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Duchenne muscular dystrophy is a serious condition caused by a recessive allele of a gene on the human X chromosome. The patients have muscles that weaken over time because they have absent or decreased dystrophin, a muscle protein. They rarely live past their twenties. How likely is it for a woman to have this condition?


A) Women can never have this condition.
B) One-fourth of the daughters of an affected man would have this condition.
C) One-half of the daughters of an affected father and a carrier mother could have this condition.
D) Only if a woman is XXX could she have this condition.

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C

Albinism is an autosomal (not sex-linked) recessive trait. A man and woman are both of normal pigmentation and have one child out of three who is albino (without melanin pigmentation) . What are the genotypes of the albino's parents?


A) One parent must be homozygous for the recessive allele; the other parent can be homozygous dominant, homozygous recessive, or heterozygous.
B) One parent must be heterozygous; the other parent can be homozygous dominant, homozygous recessive, or heterozygous.
C) Both parents must be heterozygous.
D) One parent must be homozygous dominant; the other parent must be heterozygous.
E) Both parents must be homozygous dominant.

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In certain plants, tall is dominant to short. If a heterozygous plant is crossed with a homozygous tall plant, what is the probability that the offspring will be short?


A) 1
B) 1/2
C) 1/4
D) 1/6
E) 0

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E

Which of the following is the meaning of the chromosome theory of inheritance as expressed in the early twentieth century?


A) Individuals inherit particular chromosomes attached to genes.
B) Mendelian genes are at specific loci on the chromosome and, in turn, segregate during meiosis.
C) Homologous chromosomes give rise to some genes and crossover chromosomes to other genes.
D) No more than a single pair of chromosomes can be found in a healthy normal cell.
E) Natural selection acts on certain chromosome arrays rather than on genes.

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The work of Gregor Mendel provided an answer to two prevailing hypotheses popular at the time. What were these two hypotheses?


A) Mitosis is only typical in vertebrates. Meiosis is only typical in invertebrates.
B) The two major hypotheses of the time were blending inheritance and inheritance of acquired characteristics.
C) Animals use one set of rules for inheritance, and plants use a different set.
D) Peas and other domestic plants are unsuited for studies of inheritance, but wild plants are perfectly suited.
E) Self-fertilization is the rule in plants, whereas cross-fertilization is the rule in animals.

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Cystic fibrosis affects the lungs, the pancreas, the digestive system, and other organs, resulting in symptoms ranging from breathing difficulties to recurrent infections. Which of the following terms best describes this?


A) incomplete dominance
B) multiple alleles
C) pleiotropy
D) epistasis
E) codominance

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Phenylketonuria (PKU) is a recessive human disorder in which an individual cannot appropriately metabolize the amino acid phenylalanine. This amino acid is not naturally produced by humans. Therefore, the most efficient and effective treatment is which of the following?


A) Feed them the substrate that can be metabolized into this amino acid.
B) Transfuse the patients with blood from unaffected donors.
C) Regulate the diet of the affected persons to severely limit the uptake of the amino acid.
D) Feed the patients the missing enzymes in a regular cycle, such as twice per week.
E) Feed the patients an excess of the missing product.

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Hutchinson-Gilford progeria is an exceedingly rare human genetic disorder in which there is very early senility and death, usually from coronary artery disease, at an average age of 13 years. Patients, who look very old even as children, do not live to reproduce. Which of the following represents the most likely assumption?


A) The disease is autosomal dominant.
B) The disorder will increase in frequency in successive generations within a family.
C) The disorder may be due to mutation in a single protein-coding gene.
D) Each patient will have had at least one affected grandparent or parent.

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The following question(s) refer to the pedigree chart in the accompanying figure for a family, some of whose members exhibit the dominant trait, W. Affected individuals are indicated by a dark square or circle. The following question(s)  refer to the pedigree chart in the accompanying figure for a family, some of whose members exhibit the dominant trait, W. Affected individuals are indicated by a dark square or circle.   -What is the likelihood that the progeny of IV-3 and IV-4 will have the trait? A)  0 percent B)  25 percent C)  50 percent D)  75 percent E)  100 percent -What is the likelihood that the progeny of IV-3 and IV-4 will have the trait?


A) 0 percent
B) 25 percent
C) 50 percent
D) 75 percent
E) 100 percent

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In humans, blue eyes are inherited as a recessive autosomal trait and color blindness is an X-linked recessive trait. A woman with blue eyes and normal color vision whose father was color-blind marries a man who also has normal color vision. He has brown eyes but his mother had blue eyes. Which of the following would you expect to be TRUE for their daughters?


A) One-half of their daughters will have normal color vision and brown eyes; one-half of their daughters will have normal color vision and blue eyes.
B) Their daughters will all have normal color vision and brown eyes.
C) One-fourth of their daughters will be color-blind and have blue eyes, one-fourth of their daughters will be color-blind and have brown eyes, one-fourth of their daughters will have normal color vision and blue eyes, and one-fourth of their daughters will have normal color vision and brown eyes.
D) Their daughters will all have normal color vision and have blue eyes.
E) One-half of their daughters will be color-blind and have blue eyes; one-half of their daughters will be color-blind and have brown eyes.

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A

Use the figure and the following description to answer the question(s) below. -Which of the boxes marked 1-4 correspond to plants that will be true-breeding?


A) 1 and 4 only
B) 2 and 3 only
C) 1, 2, 3, and 4
D) 1 only
E) 1 and 2 only

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Assuming independent assortment for all gene pairs, what is the probability that the following parents, AABbCc × AaBbCc, will produce an AaBbCc offspring?


A) 1/2
B) 1/16
C) 1/8
D) 3/4
E) 9/16

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Albinism is an autosomal (not sex-linked) recessive trait. A man and woman are both of normal pigmentation, but both have one parent who is albino (without melanin pigmentation) . What is the probability that their first child will be an albino?


A) 0
B) 1/8
C) 1/2
D) 1/4
E) 1/3

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Mendel accounted for the observation that traits which had disappeared in the F1 generation reappeared in the F2 generation by proposing that ________.


A) new mutations were frequently generated in the F2 progeny, "reinventing" traits that had been lost in the F1
B) the mechanism controlling the appearance of traits was different between the F1 and the F2 plants
C) traits can be dominant or recessive, and the recessive traits were obscured by the dominant ones in the F1 generation
D) members of the F1 generation had only one allele for each trait, but members of the F2 had two alleles for each trait

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