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What is the role of a tumour suppressor protein in a cell?


A) to promote cell division of abnormal cells
B) to slow or halt cell division in abnormal cells
C) to trigger DNA replication in preparation for cell division
D) to promote cell division of healthy cells

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Identify each labelled part on the illustration of the Lac operon. Identify each labelled part on the illustration of the Lac operon.    -lacZ -lacZ

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Which of the following genes encode proteins that generally stimulate cell division in normal cells?


A) proto-suppressor genes
B) proto-oncogenes
C) oncogenes
D) tumour suppressor genes

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Which term refers to a cluster of genes transcribed into a single mRNA unit in the operon model?


A) alpha genes
B) mRNA cluster
C) gene group
D) transcription unit

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Identify each labelled part on the illustration of the Lac operon. Identify each labelled part on the illustration of the Lac operon.    -operator -operator

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Why can steroid hormones trigger gene expression in a select number of different cells?


A) because only target cells allow the steroid hormone to cross the plasma membrane
B) because only the target cells have a steroid hormone response element encoded in their DNA
C) because only the target cells have the correct coactivator
D) because only the target cells have a nucleus

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In catabolite repression, what is indicated by high levels of cAMP?


A) low lactose
B) low glucose
C) high lactose
D) high glucose

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Match each term with its definition. -malignant


A) regulatory protein that activates the expression of an operon's genes
B) interfering RNA molecules originally encoded by nuclear DNA
C) process of controlling the expression of genes that takes place at the DNA level
D) regulatory protein that prevents an operon's genes from being expressed
E) inhibition of transcription via DNA methylation
F) interfering RNA molecules associated with some viral life cycles
G) tumour comprising cells that invade and disrupt the surrounding tissues
H) increases expression of an operon's genes
I) cluster of prokaryotic genes and their associated DNA regulatory sequences
J) tumour comprising undifferentiated cells that stay together in a single mass
K) spread of malignant cells through the blood or lymphatic system
L) removes a nucleosome from DNA to expose a promoter

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Where does the first general transcription factor bind to?


A) site where transcription starts
B) TATA box
C) activator
D) enhancer

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Which type of RNA is produced from genes that come from outside the cell?


A) mRNA
B) miRNA
C) tRNA
D) siRNA

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Which element(s) does RNA polymerase II bind to?


A) transcription factors bound to the promoter
B) free-floating transcription factors
C) TATA box
D) promoter sequence

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What is the primary distinction between different nucleated cells in a developing zygote?


A) the expression of a gene or group of genes
B) the genetic code of each cell
C) the number of chromosomes present in the nucleus
D) the expression of housekeeping genes

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Identify each labelled part on the illustration of the Lac operon. Identify each labelled part on the illustration of the Lac operon.    -lacI -lacI

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Which of the following are the regulatory proteins that play a role in a positive regulatory system that controls the expression of one or more genes?


A) introns
B) exons
C) activators
D) enhancers

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Suppose that you are asked to locate some mRNA masking proteins, and are given two rabbits-one male and one female-to use as your cell sources. Also suppose that you decide to do some needle biopsies of one particular tissue, and to extract the masking proteins. Which tissues or organ samples should you collect for analysis?


A) skin cells
B) testes
C) liver cells
D) ovaries

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Which of the following components of an operon is a molecule of DNA?


A) repressor
B) lactose
C) mRNA
D) operator

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Suppose that an E. coli has a mutation in its lac operon such that the Lac repressor could NOT bind the operator, even in the absence of lactose. What would be the result in terms of the function of the operon?


A) The lac operon would be transcribed, but at a high level.
B) The lac operon would be expressed only when lactose was present.
C) There would be no real impact on lac operon expression.
D) The lac operon would be transcribed, but at a low level.

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