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Exam 18: Regulation of Gene Expression

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Question 21

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A researcher found a method she could use to manipulate and quantify phosphorylation and methylation in embryonic cells in culture. One of her colleagues suggested she try increased methylation of cytosine (C) nucleotides in the DNA of promoters of a mammalian system. Which of the following results would she most likely see?

A) decreased chromatin condensation
B) activation of histone tails for enzymatic function
C) higher levels of transcription of certain genes
D) inactivation of the selected genes

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Question 22

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Under what conditions does the trp repressor block transcription of the trp operon?

A) when the repressor binds to the inducer
B) when the repressor binds to tryptophan
C) when the repressor is not bound to tryptophan
D) when the repressor is not bound to the operator

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Question 23

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Which of the following conditions is most likely to cause the lactose operon to be transcribed?

Which of the following statements best describes the characteristics of siRNA?

Which of the following statements correctly describes a characteristic of tumour-suppressor gene?

Which of the following processes would allow the detection of alternative splicing of transcripts from a given gene?

Which of the following processes destroys RNA molecules in a cell if they have a sequence complementary to an introduced double-stranded RNA?

The reason for differences in the sets of proteins expressed in a nerve and a pancreatic cell of the same individual is that nerve and pancreatic cells contain different ________.

For a repressible operon to be transcribed, which of the following conditions must occur?

There is a mutation that is found in E. coli in the repressor that results in a molecule known as a super-repressor because it represses the lac operon permanently. Which of the following characteristics would you expect to observe in such a mutant?

According to the lac operon model proposed by Jacob and Monod, what is predicted to occur if the operator is removed from the operon?

Which of the following molecules helps to "turn off" genes in a cell?

Which of the following functions does the product of the p53 gene carry out?

Cell differentiation always involves

Suppose an experimenter becomes proficient with a technique that allows her to move DNA sequences within a prokaryotic genome. If a researcher moves the operator to the far end of the operon, past the transacetylase (lacA) gene, which of the following processes would likely occur when the cell is exposed to lactose?

Absence of bicoid mRNA from a Drosophila egg leads to the absence of anterior larval body parts and mirror-image duplication of posterior parts. This is evidence that the product of the bicoid gene

Forms of the Ras protein found in tumours usually cause which of the following events to occur?

Muscle cells differ from nerve cells mainly because they

Which of the following statements correctly describes the primary difference between enhancers and proximal control elements?

Suppose an experimenter becomes proficient with a technique that allows her to move DNA sequences within a prokaryotic genome. If a researcher moves the promoter for the lac operon to the region between the beta galactosidase (lacZ) gene and the permease (lacY) gene, which of the following results would be most likely?