Question 1

In which cells do erasure and re-establishment of imprinting marks typically not occur?

Accepted Answer

A)   Nurse cells
B)   Sperm cells
C)   Oocytes
D)   Somatic cells

Question 2

Monoallelic expression is associated with which of the following?

Accepted Answer

A)   X-inactivation
B)   Genomic imprinting
C)   Maternal inheritance
D)   Extranuclear inheritance

Question 3

In the Igf2 gene, which allele is expressed?

Accepted Answer

A)   Paternal
B)   Maternal
C)   Both maternal and paternal
D)   Neither allele is expressed

Question 4

What is thought to be the origin of mitochondria and chloroplasts?

Accepted Answer

A)   Cyanobacteria for mitochondria, purple bacteria for chloroplasts
B)   Purple bacteria for mitochondria, fungi for chloroplasts
C)   Purple bacteria for mitochondria, cyanobacteria for chloroplasts
D)   Algae for mitochondria, cyanobacteria for chloroplasts

Question 5

Which of the following is false regarding human mtDNA?

Accepted Answer

A)   It is around 17,000 bp in length.
B)   It is a linear chromosome.
C)   Multiple copies exist in each mitochondria.
D)   It mostly contains rRNA and tRNA genes, and genes for mitochondrial function.

Question 6

The inheritance patterns of genetic material that is not contained in the nucleus of the cell is called ________.

Accepted Answer

A)   extranuclear inheritance
B)   maternal effect
C)   imprinting
D)   nuclear
E)   epigenetic

Question 7

What is the molecular mechanism for imprinting a gene?

Accepted Answer

A)   Acetylation
B)   Nitration
C)   Phosphorylation
D)   Methylation

Question 8

Heteroplasmy is associated with inheritance patterns involving

Accepted Answer

A)   nuclear.
B)   paternal DNA.
C)   chloroplasts.
D)   ribosomes.
E)   imprinted.

Question 9

Who originally identified a highly condensed structure in the interphase of nuclei?

Accepted Answer

A)   Lyon
B)   Barr
C)   Ohno
D)   None of the answers are correct

Question 10

In maternal effect, the ________ of the mother determines the ________ of the offspring.

Accepted Answer

A)   phenotype, genotype
B)   genotype, phenotype
C)   rRNA, tRNA
D)   imprinting, genotype

Question 11

A modification that occurs to a nuclear gene that alters gene expression without modifying the DNA sequence is called ________ inheritance.

Accepted Answer

A)   extranuclear
B)   cytoplasmic
C)   maternal effect
D)   epigenetic
E)   nuclear

Question 12

Which diseases are associated with imprinting?

Accepted Answer

A)   Angelman Syndrome
B)   LHON
C)   Alzheimer's Disease
D)   All of the answers are correct

Question 13

Who is largely responsible for proposing the endosymbiosis theory?

Accepted Answer

A)   Schimper, Wallin, Margulis
B)   Lyon, Margulis, Schimper
C)   Schimper, Wallin, Barr
D)   Barr, Lyon, Margulis

Question 14

The inheritance of leaf pigmentation in the four-o'clock plant Mirabilis jalapa is an example of ________.

Accepted Answer

A)   maternal effect
B)   maternal inheritance
C)   epigenetic inheritance
D)   imprinting

Question 15

A symbiotic relationship where one organism lives inside another species is called ________.

Accepted Answer

A)   cytoplasmic inheritance
B)   heteroplasmy
C)   paternal leakage
D)   endosymbiosis

Question 16

The Lyon hypothesis attempts to explain the molecular mechanism of ________.

Accepted Answer

A)   X-inactivation
B)   genomic imprinting
C)   maternal inheritance
D)   extranuclear inheritance

Question 17

Dosage compensation offsets the problems associated with differences in the number of ________ chromosomes in many species.

Accepted Answer

A)   cytoplasmic
B)   autosome
C)   sex
D)   extranuclear
E)   mitochondrial C

Question 18

If the sperm cell contributes mitochondria to the oocyte, it is called ________.

Accepted Answer

A)   paternal leakage
B)   maternal leakage
C)   paternal inheritance
D)   mitochondria
E)   imprinting

Question 19

mtDNA stands for ________ and cpDNA stands for ________.

Accepted Answer

A)   extranuclear DNA, cytoplasmic DNA
B)   maternal DNA, paternal DNA
C)   marked DNA, copied DNA
D)   nuclear, cytoplasmic
E)   mitochondrial DNA, chloroplast DNA E

Question 20

What is a disease associated with extra nuclear inheritance?

Accepted Answer

A)   Angelman Syndrome
B)   Prader-Willi Syndrome
C)   LHON
D)   Muscular Dystrophy C

Exam 5: Non-Mendelian Inheritance

In which cells do erasure and re-establishment of imprinting marks typically not occur?

Correct AnswerverifiedShow Answer

Monoallelic expression is associated with which of the following?

Correct AnswerverifiedShow Answer

In the Igf2 gene, which allele is expressed?

Correct AnswerverifiedShow Answer

What is thought to be the origin of mitochondria and chloroplasts?

Correct AnswerverifiedShow Answer

Which of the following is false regarding human mtDNA?

Correct AnswerverifiedShow Answer

The inheritance patterns of genetic material that is not contained in the nucleus of the cell is called ________.

Correct AnswerverifiedShow Answer

What is the molecular mechanism for imprinting a gene?

Correct AnswerverifiedShow Answer

Heteroplasmy is associated with inheritance patterns involving

Correct AnswerverifiedShow Answer

Who originally identified a highly condensed structure in the interphase of nuclei?

Correct AnswerverifiedShow Answer

In maternal effect, the ________ of the mother determines the ________ of the offspring.

Correct AnswerverifiedShow Answer

A modification that occurs to a nuclear gene that alters gene expression without modifying the DNA sequence is called ________ inheritance.

Correct AnswerverifiedShow Answer

Which diseases are associated with imprinting?

Correct AnswerverifiedShow Answer

Who is largely responsible for proposing the endosymbiosis theory?

Correct AnswerverifiedShow Answer

The inheritance of leaf pigmentation in the four-o'clock plant Mirabilis jalapa is an example of ________.

Correct AnswerverifiedShow Answer

A symbiotic relationship where one organism lives inside another species is called ________.

Correct AnswerverifiedShow Answer

The Lyon hypothesis attempts to explain the molecular mechanism of ________.

Correct AnswerverifiedShow Answer

Dosage compensation offsets the problems associated with differences in the number of ________ chromosomes in many species.

Correct AnswerverifiedC

If the sperm cell contributes mitochondria to the oocyte, it is called ________.

Correct AnswerverifiedShow Answer

mtDNA stands for ________ and cpDNA stands for ________.

Correct AnswerverifiedE

What is a disease associated with extra nuclear inheritance?

Correct AnswerverifiedC

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In maternal effect, the of the mother determines the of the offspring.

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C

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mtDNA stands for and cpDNA stands for .

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E

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C