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Exam 8: DNA- the Chemical Nature of the Gene

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Question 21

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A double-stranded DNA molecule of 50 base pairs contains 15 cytosine bases (C) , how many thymine bases will it have?

A) 10
B) 15
C) 30
D) 35
E) 60

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Question 22

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Indicate which of the following statements is FALSE.

A) Covalent bonds connect nucleotides in a strand; noncovalent interactions hold strands into a double-stranded structure.
B) Uracil is similar to thymine except that uracil lacks a methyl group on the carbon at position 5 on the carbon-nitrogen ring.
C) Frederick Griffith demonstrated that a transforming chemical from dead bacteria could change the genetic information of living bacteria.
D) Avery, MacLeod, and McCarty showed that DNA is the genetic information of cells and that RNA is the genetic information of viruses.
E) The pyrimidine bases in nucleic acids are cytosine, thymine, and uracil.

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Question 23

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DNA is said to be like a ladder where _____ connected by _____ bonds make up the sides of the ladder and the _____ connected by _____ bonds make up the rungs of the ladder.

Which of the following has repetitive DNA and heterochromatin?

If a nucleic acid is found to contain 20% A and 20% T, the molecule is probably:

How does the organization of the eukaryotic chromosome differ from the organization of a bacterial chromosome? Include in your

Which circle shows a bond that would also be found in an RNA transcribed from one strand of this DNA?

How does histone acetylation affect chromatin?

Imagine you forgot to cap your DNA sample and it became desiccated (dried out) .What form would the DNA take?

A tRNA gene is an example of which type of DNA sequence in eukaryotes?

Hershey and Chase determined whether DNA or protein was the genetic material in bacteriophages.What isotope did they use to label the viral protein?

You are a research assistant in a lab that studies nucleic acids.Your advisor gave you four tubes for analysis.Each of these tubes differs in its contents by the source of its nucleic acids: mouse cytoplasm (single-stranded RNA) , yeast nuclei (double-stranded DNA) , rotavirus (double-stranded RNA) , and parvovirus (single-stranded DNA) .The approximate nucleotide base composition of each sample is given in the table below. Which tube MOST likely contains mouse cytoplasm?

While doing research on deep-sea vents, you discover a very simple new life form.After some initial analysis you find that this life form contains small fragments of DNA, small complementary RNA fragments, and proteins.Fortuitously, you collected two strains, one that is purple and one that is yellow.What experiments would you perform to determine which of these three cellular constituents serve as the genetic material in your new organism?

If a bacterial chromosome were inserted into a eukaryotic cell, would it be stable? Would it segregate like eukaryotic chromosomes do during mitosis and meiosis? Why or why not?

Which of the following is an example of an epigenetic change in eukaryotes?

If a DNA molecule is 30% cytosine (C) , what is the percentage of guanine (G) ?

There are some genomes that have been reported to be positively coiled instead of negatively supercoiled, which is the status of most genomes that we have studied.The genomes that are positively supercoiled seem to belong to viruses and cells that exist at very high temperatures.Why might positive supercoiling be an advantage at high temperatures?

Which of the following is NOT characteristic of A-form DNA compared to B- or Z-form DNA?

A ribosomal RNA gene is an example of which type of DNA sequence in eukaryotes?

Which diagram shows a nucleotide with a purine base?